Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice

Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring p...

Full description

Bibliographic Details
Main Authors: Carlos González-Sánchez, Juan-Carlos Fraile, Javier Pérez-Turiel, Ellen Damm, Jochen G. Schneider, Heiko Zimmermann, Daniel Schmitt, Frank R. Ihmig
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/16/7/1052
_version_ 1811298268571762688
author Carlos González-Sánchez
Juan-Carlos Fraile
Javier Pérez-Turiel
Ellen Damm
Jochen G. Schneider
Heiko Zimmermann
Daniel Schmitt
Frank R. Ihmig
author_facet Carlos González-Sánchez
Juan-Carlos Fraile
Javier Pérez-Turiel
Ellen Damm
Jochen G. Schneider
Heiko Zimmermann
Daniel Schmitt
Frank R. Ihmig
author_sort Carlos González-Sánchez
collection DOAJ
description Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown.
first_indexed 2024-04-13T06:16:57Z
format Article
id doaj.art-1916b3a727a3492b9115d255da7279c4
institution Directory Open Access Journal
issn 1424-8220
language English
last_indexed 2024-04-13T06:16:57Z
publishDate 2016-07-01
publisher MDPI AG
record_format Article
series Sensors
spelling doaj.art-1916b3a727a3492b9115d255da7279c42022-12-22T02:58:47ZengMDPI AGSensors1424-82202016-07-01167105210.3390/s16071052s16071052Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory MiceCarlos González-Sánchez0Juan-Carlos Fraile1Javier Pérez-Turiel2Ellen Damm3Jochen G. Schneider4Heiko Zimmermann5Daniel Schmitt6Frank R. Ihmig7Fraunhofer-Institut fuer BiomedizinischeTechnik (IBMT), Sulzbach/Saar 66280, GermanyITAP—Universidad de Valladolid, Paseo del Cauce 59, Valladolid 47011, SpainITAP—Universidad de Valladolid, Paseo del Cauce 59, Valladolid 47011, SpainLuxembourg Centre for Systems Biomedicine, University of Luxembourg Esch-sur-Alzette L-4362, Luxembourg and Internal Medicine II, Saarland University Medical Center, Homburg 66421, GermanyLuxembourg Centre for Systems Biomedicine, University of Luxembourg Esch-sur-Alzette L-4362, Luxembourg and Internal Medicine II, Saarland University Medical Center, Homburg 66421, GermanyFraunhofer-Institut fuer BiomedizinischeTechnik (IBMT), Sulzbach/Saar 66280, GermanyFraunhofer-Institut fuer BiomedizinischeTechnik (IBMT), Sulzbach/Saar 66280, GermanyFraunhofer-Institut fuer BiomedizinischeTechnik (IBMT), Sulzbach/Saar 66280, GermanyAnimal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown.http://www.mdpi.com/1424-8220/16/7/1052non-invasive sensorcapacitive sensorsphysiological signals in micestress in mice
spellingShingle Carlos González-Sánchez
Juan-Carlos Fraile
Javier Pérez-Turiel
Ellen Damm
Jochen G. Schneider
Heiko Zimmermann
Daniel Schmitt
Frank R. Ihmig
Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
Sensors
non-invasive sensor
capacitive sensors
physiological signals in mice
stress in mice
title Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_full Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_fullStr Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_full_unstemmed Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_short Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_sort capacitive sensing for non invasive breathing and heart monitoring in non restrained non sedated laboratory mice
topic non-invasive sensor
capacitive sensors
physiological signals in mice
stress in mice
url http://www.mdpi.com/1424-8220/16/7/1052
work_keys_str_mv AT carlosgonzalezsanchez capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT juancarlosfraile capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT javierperezturiel capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT ellendamm capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT jochengschneider capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT heikozimmermann capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT danielschmitt capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice
AT frankrihmig capacitivesensingfornoninvasivebreathingandheartmonitoringinnonrestrainednonsedatedlaboratorymice