ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance

ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance

Abstract Accumulating evidence demonstrates that the activity regulation of ELK3, a member of the E26 transformation-specific oncogene family, is critical to regulating cell proliferation, migration, and survival in human cancers. However, the molecular mechanisms of how ELK3 induces chemoresistance...

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Main Authors: Cheol-Jung Lee, Heejung Lee, Seo Ree Kim, Soo-Bin Nam, Ga-Eun Lee, Kyeong Eun Yang, Guk Jin Lee, Sang Hoon Chun, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Sung-Jun Cho, Yong-Yeon Cho
Format: Article
Language:English
Published: Nature Publishing Group 2024-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06647-0

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https://doi.org/10.1038/s41419-024-06647-0

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