ELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance
Abstract Accumulating evidence demonstrates that the activity regulation of ELK3, a member of the E26 transformation-specific oncogene family, is critical to regulating cell proliferation, migration, and survival in human cancers. However, the molecular mechanisms of how ELK3 induces chemoresistance...
Main Authors: | Cheol-Jung Lee, Heejung Lee, Seo Ree Kim, Soo-Bin Nam, Ga-Eun Lee, Kyeong Eun Yang, Guk Jin Lee, Sang Hoon Chun, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Sung-Jun Cho, Yong-Yeon Cho |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-04-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-024-06647-0 |
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