In Vitro Formation of 8-hydroxy-2-deoxyguanosine (8-OHdG) in Calf Thymus DNA upon Treatment of 2-deoxyguanosine with Propyl Gallate and 2,6-di-tert-butyl-p-benzoquinone

Oxidative DNA damage caused by propyl gallate (PG) and 2,6-di-tert-butyl-p-benzoquinone (BHT-quinone, a metabolite of butylated hydroxytoluene (BHT)) was analyzed from the 8-hydroxy-2¢-deoxyguanosine (8-OHdG) formation in calf thymus DNA and DNA base, 2¢-deoxyguanosine (dG). PG in the presence of Cu...

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Bibliographic Details
Main Authors: Budiawan Budiawan, Dwi Retno Widiastuti
Format: Article
Language:English
Published: Universitas Indonesia 2015-12-01
Series:Makara Journal of Science
Subjects:
Online Access:http://journal.ui.ac.id/index.php/science/article/view/5171/3481