The study of acute toxicity of burdock root tincture
Aim. Burdock root is used in scientific medicine as diuretic, choleretic, antipyretic, anti-inflammatory, antibacterial, antifungal, desensitizing, immunostimulatory, antioxidant and metabolism improving remedy. To study acute toxicity of the Burdock root tincture (extractant is a 40% ethanol) at th...
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| Format: | Article |
| Language: | English |
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Zaporozhye State Medical University
2014-12-01
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| Series: | Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki |
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| Online Access: | http://pharmed.zsmu.edu.ua/article/view/33867/30409 |
| Summary: | Aim. Burdock root is used in scientific medicine as diuretic, choleretic, antipyretic, anti-inflammatory, antibacterial, antifungal, desensitizing, immunostimulatory, antioxidant and metabolism improving remedy. To study acute toxicity of the Burdock root tincture (extractant is a 40% ethanol) at the terms of single internally gastric injection at 5 ml/kg, 15 ml/кg and 20 ml/kg dose, 84 white rats and 84 mice of both sexes (14 groups which consist of 6 animals) have been used.
Methods and results. The determination of acute toxicity has been conducted using Kerber method. It has been set that the Burdock root tincture belongs to VІ class of toxicity (comparing to harmless substances) in obedience to the generally accepted toxicological classification of substances.
Conclusion. This shows that future research of Burdock root tincture is a perspective direction. |
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| ISSN: | 2306-8094 2409-2932 |