GDE6 promotes progenitor identity in the vertebrate neural tube

GDE6 promotes progenitor identity in the vertebrate neural tube

The generation of neurons in the central nervous system is a complex, stepwise process necessitating the coordinated activity of mitotic progenitors known as radial glia. Following neural tube closure, radial glia undergo a period of active proliferation to rapidly expand their population, creating...

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Bibliographic Details
Main Authors: Madeline McKean, Francesca R. Napoli, Tahira Hasan, Thea Joseph, Alison Wheeler, Katherine Beebe, Stephanie Soriano-Cruz, Minori Kawano, Clinton Cave
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Neuroscience
Subjects:
GDE6
neural tube development
patterning
neurogenesis
hyperplasia
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1047767/full

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