Bi-glandular and persistent enterovirus infection and distinct changes of the pancreas in slowly progressive type 1 diabetes mellitus

Bi-glandular and persistent enterovirus infection and distinct changes of the pancreas in slowly progressive type 1 diabetes mellitus

Abstract In slowly progressive type 1 diabetes mellitus (SPIDDM), the pancreas shows sustained islet inflammation, pancreatitis, pancreatic acinar cell metaplasia/dysplasia (ADM), and intraepithelial neoplasia (PanIN), a precancerous lesion. The mechanisms underlying these changes remain unclear. Th...

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Bibliographic Details
Main Authors: Tomoyasu Fukui, Tetsuro Kobayashi, Erika Jimbo, Kaoru Aida, Akira Shimada, Yoichi Oikawa, Yasumichi Mori, Takeshi Fujii, Rikako Koyama, Kazuhiko Kobayashi, Akira Takeshita, Soroku Yagihashi
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33011-7

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