Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children
Multisystem Inflammatory Syndrome in Children (MIS-C) is recognized as a life threatening complication of Coronavirus disease (COVID-19) in children which can affect major systems such as cardiovascular, respiratory, blood and coagulation, renal, and nervous system. Mild cases of MIS-C can be follow...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2021-09-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-17103-en.html |
| _version_ | 1828069789650649088 |
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| author | Leila Shahbaznejad Azin Hajialibeig Mohammad Reza Navaeifar Zahra Doorandish Mohammad Sadegh Rezai |
| author_facet | Leila Shahbaznejad Azin Hajialibeig Mohammad Reza Navaeifar Zahra Doorandish Mohammad Sadegh Rezai |
| author_sort | Leila Shahbaznejad |
| collection | DOAJ |
| description | Multisystem Inflammatory Syndrome in Children (MIS-C) is recognized as a life threatening complication of Coronavirus disease (COVID-19) in children which can affect major systems such as cardiovascular, respiratory, blood and coagulation, renal, and nervous system. Mild cases of MIS-C can be followed up closely, but, severe illnesses that require hospitalization or pediatric intensive care are also common. Treatment of these patients includes supportive measures to improve the function of vital organs such as the heart and arteries, respiration, and kidneys. Antiviral therapy is recommended in patients with clear involvement of the respiratory system. Treatment with empirical antibiotics and drugs effective in suppressing or modulating the immune system such as steroids in various doses, intravenous immunoglobulins, biologic drugs, anticoagulants, and antiplatelets are recommended. In case of shock or decreased cardiac function, vasopressor drugs are suggested along with supportive measures to maintain tissue perfusions such as albumin and compressed red blood cells. Timely diagnosis and appropriate treatments improve the patient's condition and evaluation of long-term complications of this disease should be done. |
| first_indexed | 2024-04-11T00:25:49Z |
| format | Article |
| id | doaj.art-1923daa6b19d4ef1bbec8a9d0bbd0833 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-11T00:25:49Z |
| publishDate | 2021-09-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-1923daa6b19d4ef1bbec8a9d0bbd08332023-01-08T07:53:34ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792021-09-0131200173186Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in ChildrenLeila Shahbaznejad0Azin Hajialibeig1Mohammad Reza Navaeifar2Zahra Doorandish3Mohammad Sadegh Rezai4 Assistant Profesor, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Pediatrician, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Assistant Profesor, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Pediatric Resident, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran Profesor, Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Multisystem Inflammatory Syndrome in Children (MIS-C) is recognized as a life threatening complication of Coronavirus disease (COVID-19) in children which can affect major systems such as cardiovascular, respiratory, blood and coagulation, renal, and nervous system. Mild cases of MIS-C can be followed up closely, but, severe illnesses that require hospitalization or pediatric intensive care are also common. Treatment of these patients includes supportive measures to improve the function of vital organs such as the heart and arteries, respiration, and kidneys. Antiviral therapy is recommended in patients with clear involvement of the respiratory system. Treatment with empirical antibiotics and drugs effective in suppressing or modulating the immune system such as steroids in various doses, intravenous immunoglobulins, biologic drugs, anticoagulants, and antiplatelets are recommended. In case of shock or decreased cardiac function, vasopressor drugs are suggested along with supportive measures to maintain tissue perfusions such as albumin and compressed red blood cells. Timely diagnosis and appropriate treatments improve the patient's condition and evaluation of long-term complications of this disease should be done.http://jmums.mazums.ac.ir/article-1-17103-en.htmlcovid-19multi-system inflammatory syndrome in childrensteroids |
| spellingShingle | Leila Shahbaznejad Azin Hajialibeig Mohammad Reza Navaeifar Zahra Doorandish Mohammad Sadegh Rezai Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children Journal of Mazandaran University of Medical Sciences covid-19 multi-system inflammatory syndrome in children steroids |
| title | Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children |
| title_full | Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children |
| title_fullStr | Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children |
| title_full_unstemmed | Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children |
| title_short | Diagnosis and Treatment of Multisystem Inflammatory Syndrome Following COVID-19 in Children |
| title_sort | diagnosis and treatment of multisystem inflammatory syndrome following covid 19 in children |
| topic | covid-19 multi-system inflammatory syndrome in children steroids |
| url | http://jmums.mazums.ac.ir/article-1-17103-en.html |
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