Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening

Among the various chemoresistive gas sensing properties studied so far, the sensing response reproducibility, i.e., the capability to reproduce a device with the same sensing performance, has been poorly investigated. However, the reproducibility of the gas sensing performance is of fundamental impo...

Full description

Bibliographic Details
Main Authors: Andrea Gaiardo, Giulia Zonta, Sandro Gherardi, Cesare Malagù, Barbara Fabbri, Matteo Valt, Lia Vanzetti, Nicolò Landini, Davide Casotti, Giuseppe Cruciani, Michele Della Ciana, Vincenzo Guidi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/20/5910
_version_ 1797550437220483072
author Andrea Gaiardo
Giulia Zonta
Sandro Gherardi
Cesare Malagù
Barbara Fabbri
Matteo Valt
Lia Vanzetti
Nicolò Landini
Davide Casotti
Giuseppe Cruciani
Michele Della Ciana
Vincenzo Guidi
author_facet Andrea Gaiardo
Giulia Zonta
Sandro Gherardi
Cesare Malagù
Barbara Fabbri
Matteo Valt
Lia Vanzetti
Nicolò Landini
Davide Casotti
Giuseppe Cruciani
Michele Della Ciana
Vincenzo Guidi
author_sort Andrea Gaiardo
collection DOAJ
description Among the various chemoresistive gas sensing properties studied so far, the sensing response reproducibility, i.e., the capability to reproduce a device with the same sensing performance, has been poorly investigated. However, the reproducibility of the gas sensing performance is of fundamental importance for the employment of these devices in on-field applications, and to demonstrate the reliability of the process development. This sensor property became crucial for the preparation of medical diagnostic tools, in which the use of specific chemoresistive gas sensors along with a dedicated algorithm can be used for screening diseases. In this work, the reproducibility of SmFeO<sub>3</sub> perovskite-based gas sensors has been investigated. A set of four SmFeO<sub>3</sub> devices, obtained from the same screen-printing deposition, have been tested in laboratory with both controlled concentrations of CO and biological fecal samples. The fecal samples tested were employed in the clinical validation protocol of a prototype for non-invasive colorectal cancer prescreening. Sensors showed a high reproducibility degree, with an error lower than 2% of the response value for the test with CO and lower than 6% for fecal samples. Finally, the reproducibility of the SmFeO<sub>3</sub> sensor response and recovery times for fecal samples was also evaluated.
first_indexed 2024-03-10T15:29:16Z
format Article
id doaj.art-192465c51a3242f39aee2857f79ff56c
institution Directory Open Access Journal
issn 1424-8220
language English
last_indexed 2024-03-10T15:29:16Z
publishDate 2020-10-01
publisher MDPI AG
record_format Article
series Sensors
spelling doaj.art-192465c51a3242f39aee2857f79ff56c2023-11-20T17:44:16ZengMDPI AGSensors1424-82202020-10-012020591010.3390/s20205910Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer ScreeningAndrea Gaiardo0Giulia Zonta1Sandro Gherardi2Cesare Malagù3Barbara Fabbri4Matteo Valt5Lia Vanzetti6Nicolò Landini7Davide Casotti8Giuseppe Cruciani9Michele Della Ciana10Vincenzo Guidi11MNF—Micro Nano Facility, Bruno Kessler Foundation, Via Sommarive 18, 38123 Trento, ItalySCENT S.r.l., Via Quadrifoglio 11, 44124 Ferrara, ItalySCENT S.r.l., Via Quadrifoglio 11, 44124 Ferrara, ItalySCENT S.r.l., Via Quadrifoglio 11, 44124 Ferrara, ItalyDepartment of Physics and Earth Sciences, University of Ferrara, Via Saragat 1, 44122 Ferrara, ItalyDepartment of Physics and Earth Sciences, University of Ferrara, Via Saragat 1, 44122 Ferrara, ItalyMNF—Micro Nano Facility, Bruno Kessler Foundation, Via Sommarive 18, 38123 Trento, ItalySCENT S.r.l., Via Quadrifoglio 11, 44124 Ferrara, ItalyINFN Section of Ferrara, Via Saragat 1/c, 44122 Ferrara, ItalyDepartment of Physics and Earth Sciences, University of Ferrara, Via Saragat 1, 44122 Ferrara, ItalyDepartment of Physics and Earth Sciences, University of Ferrara, Via Saragat 1, 44122 Ferrara, ItalyDepartment of Physics and Earth Sciences, University of Ferrara, Via Saragat 1, 44122 Ferrara, ItalyAmong the various chemoresistive gas sensing properties studied so far, the sensing response reproducibility, i.e., the capability to reproduce a device with the same sensing performance, has been poorly investigated. However, the reproducibility of the gas sensing performance is of fundamental importance for the employment of these devices in on-field applications, and to demonstrate the reliability of the process development. This sensor property became crucial for the preparation of medical diagnostic tools, in which the use of specific chemoresistive gas sensors along with a dedicated algorithm can be used for screening diseases. In this work, the reproducibility of SmFeO<sub>3</sub> perovskite-based gas sensors has been investigated. A set of four SmFeO<sub>3</sub> devices, obtained from the same screen-printing deposition, have been tested in laboratory with both controlled concentrations of CO and biological fecal samples. The fecal samples tested were employed in the clinical validation protocol of a prototype for non-invasive colorectal cancer prescreening. Sensors showed a high reproducibility degree, with an error lower than 2% of the response value for the test with CO and lower than 6% for fecal samples. Finally, the reproducibility of the SmFeO<sub>3</sub> sensor response and recovery times for fecal samples was also evaluated.https://www.mdpi.com/1424-8220/20/20/5910nanostructured SmFeO<sub>3</sub> perovskitechemoresistive gas sensorsgas sensor reproducibilityCRC screeningmedical diagnostic tool
spellingShingle Andrea Gaiardo
Giulia Zonta
Sandro Gherardi
Cesare Malagù
Barbara Fabbri
Matteo Valt
Lia Vanzetti
Nicolò Landini
Davide Casotti
Giuseppe Cruciani
Michele Della Ciana
Vincenzo Guidi
Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening
Sensors
nanostructured SmFeO<sub>3</sub> perovskite
chemoresistive gas sensors
gas sensor reproducibility
CRC screening
medical diagnostic tool
title Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening
title_full Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening
title_fullStr Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening
title_full_unstemmed Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening
title_short Nanostructured SmFeO<sub>3</sub> Gas Sensors: Investigation of the Gas Sensing Performance Reproducibility for Colorectal Cancer Screening
title_sort nanostructured smfeo sub 3 sub gas sensors investigation of the gas sensing performance reproducibility for colorectal cancer screening
topic nanostructured SmFeO<sub>3</sub> perovskite
chemoresistive gas sensors
gas sensor reproducibility
CRC screening
medical diagnostic tool
url https://www.mdpi.com/1424-8220/20/20/5910
work_keys_str_mv AT andreagaiardo nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT giuliazonta nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT sandrogherardi nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT cesaremalagu nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT barbarafabbri nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT matteovalt nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT liavanzetti nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT nicololandini nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT davidecasotti nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT giuseppecruciani nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT micheledellaciana nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening
AT vincenzoguidi nanostructuredsmfeosub3subgassensorsinvestigationofthegassensingperformancereproducibilityforcolorectalcancerscreening