Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

Abstract Background Epidemiological studies of DNA methylation profiles may uncover the molecular mechanisms through which genetic and environmental factors contribute to the risk of multifactorial diseases. There are two types of commonly used DNA bioresources, peripheral blood cells (PBCs) and EBV...

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Bibliographic Details
Main Authors: Itsuki Taniguchi, Chihiro Iwaya, Keizo Ohnaka, Hiroki Shibata, Ken Yamamoto
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Human Genomics
Subjects:
DNA methylation
Lymphoblastoid cell lines
Epigenome-wide analysis
Epigenetic epidemiology
Human methylation array
Online Access:http://link.springer.com/article/10.1186/s40246-017-0106-6

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