Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality
Background and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we exami...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2018-10-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2018.00827/full |
| _version_ | 1818476470582902784 |
|---|---|
| author | Runhua Zhang Runhua Zhang Runhua Zhang Runhua Zhang Gaifen Liu Gaifen Liu Gaifen Liu Gaifen Liu Yong Jiang Yong Jiang Yong Jiang Yong Jiang Gang Li Yuesong Pan Yuesong Pan Yuesong Pan Yuesong Pan Yilong Wang Yilong Wang Yilong Wang Yilong Wang Zaihua Wei Jing Wang Yongjun Wang Yongjun Wang Yongjun Wang Yongjun Wang |
| author_facet | Runhua Zhang Runhua Zhang Runhua Zhang Runhua Zhang Gaifen Liu Gaifen Liu Gaifen Liu Gaifen Liu Yong Jiang Yong Jiang Yong Jiang Yong Jiang Gang Li Yuesong Pan Yuesong Pan Yuesong Pan Yuesong Pan Yilong Wang Yilong Wang Yilong Wang Yilong Wang Zaihua Wei Jing Wang Yongjun Wang Yongjun Wang Yongjun Wang Yongjun Wang |
| author_sort | Runhua Zhang |
| collection | DOAJ |
| description | Background and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we examined the short-term effects of particulate matter <2.5 μm in diameter (PM2.5) and particulate matter <10 μm in diameter (PM10) on ischemic stroke mortality and hemorrhagic stroke mortality in Beijing, China.Methods: We used an ecological study design and quasi-Poisson generalized additive models to evaluate the association of PM2.5 and PM10 and cerebrovascular diseases mortality, as well as ischemic- and hemorrhagic stroke mortality. In the model, we controlled long-term and season trends, temperature, and relative humidity, the day of the week and air pollution. For cerebrovascular diseases mortality, we examined the effects stratified by sex and age with different lag days.Results: A total of 48,122 deaths for cerebrovascular disease (32,799 deaths for ischemic stroke and 13,051 deaths for hemorrhagic stroke) were included in the study. PM2.5 was associated with stroke mortality. The 10 μg/m3 increase of PM2.5 was associated with the increase of mortality, 0.27% (95% CI, 0.12–0.43%) for cerebrovascular diseases, 0.23% (95% CI, 0.04–0.42%) for ischemic stroke and 0.37% (95% CI, 0.07–0.67%) for hemorrhagic stroke -. The associations between PM10 and mortality were also detected for cerebrovascular diseases and ischemic stroke, but not in hemorrhagic stroke. The stratified analysis suggested age and gender did not modify the effects of PM on mortality significantly.Conclusions: Our study suggested that short-term exposure to ambient PM was associated with the risk of stroke mortality. |
| first_indexed | 2024-12-10T09:26:08Z |
| format | Article |
| id | doaj.art-1928f49883c340fba3153098fc95661e |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-10T09:26:08Z |
| publishDate | 2018-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-1928f49883c340fba3153098fc95661e2022-12-22T01:54:30ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-10-01910.3389/fneur.2018.00827406874Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke MortalityRunhua Zhang0Runhua Zhang1Runhua Zhang2Runhua Zhang3Gaifen Liu4Gaifen Liu5Gaifen Liu6Gaifen Liu7Yong Jiang8Yong Jiang9Yong Jiang10Yong Jiang11Gang Li12Yuesong Pan13Yuesong Pan14Yuesong Pan15Yuesong Pan16Yilong Wang17Yilong Wang18Yilong Wang19Yilong Wang20Zaihua Wei21Jing Wang22Yongjun Wang23Yongjun Wang24Yongjun Wang25Yongjun Wang26Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaCenter of Stroke, Beijing Institute for Brain Disorders, Beijing, ChinaBeijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaCenter of Stroke, Beijing Institute for Brain Disorders, Beijing, ChinaBeijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaCenter of Stroke, Beijing Institute for Brain Disorders, Beijing, ChinaBeijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, ChinaBeijing Center for Diseases Prevention and Control, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaCenter of Stroke, Beijing Institute for Brain Disorders, Beijing, ChinaBeijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaCenter of Stroke, Beijing Institute for Brain Disorders, Beijing, ChinaBeijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, ChinaBeijing Center for Diseases Prevention and Control, Beijing, ChinaBeijing Center for Diseases Prevention and Control, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaCenter of Stroke, Beijing Institute for Brain Disorders, Beijing, ChinaBeijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, ChinaBackground and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we examined the short-term effects of particulate matter <2.5 μm in diameter (PM2.5) and particulate matter <10 μm in diameter (PM10) on ischemic stroke mortality and hemorrhagic stroke mortality in Beijing, China.Methods: We used an ecological study design and quasi-Poisson generalized additive models to evaluate the association of PM2.5 and PM10 and cerebrovascular diseases mortality, as well as ischemic- and hemorrhagic stroke mortality. In the model, we controlled long-term and season trends, temperature, and relative humidity, the day of the week and air pollution. For cerebrovascular diseases mortality, we examined the effects stratified by sex and age with different lag days.Results: A total of 48,122 deaths for cerebrovascular disease (32,799 deaths for ischemic stroke and 13,051 deaths for hemorrhagic stroke) were included in the study. PM2.5 was associated with stroke mortality. The 10 μg/m3 increase of PM2.5 was associated with the increase of mortality, 0.27% (95% CI, 0.12–0.43%) for cerebrovascular diseases, 0.23% (95% CI, 0.04–0.42%) for ischemic stroke and 0.37% (95% CI, 0.07–0.67%) for hemorrhagic stroke -. The associations between PM10 and mortality were also detected for cerebrovascular diseases and ischemic stroke, but not in hemorrhagic stroke. The stratified analysis suggested age and gender did not modify the effects of PM on mortality significantly.Conclusions: Our study suggested that short-term exposure to ambient PM was associated with the risk of stroke mortality.https://www.frontiersin.org/article/10.3389/fneur.2018.00827/fullparticulate matterriskstrokeischemichemorrhagicmortality |
| spellingShingle | Runhua Zhang Runhua Zhang Runhua Zhang Runhua Zhang Gaifen Liu Gaifen Liu Gaifen Liu Gaifen Liu Yong Jiang Yong Jiang Yong Jiang Yong Jiang Gang Li Yuesong Pan Yuesong Pan Yuesong Pan Yuesong Pan Yilong Wang Yilong Wang Yilong Wang Yilong Wang Zaihua Wei Jing Wang Yongjun Wang Yongjun Wang Yongjun Wang Yongjun Wang Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality Frontiers in Neurology particulate matter risk stroke ischemic hemorrhagic mortality |
| title | Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality |
| title_full | Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality |
| title_fullStr | Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality |
| title_full_unstemmed | Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality |
| title_short | Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality |
| title_sort | acute effects of particulate air pollution on ischemic stroke and hemorrhagic stroke mortality |
| topic | particulate matter risk stroke ischemic hemorrhagic mortality |
| url | https://www.frontiersin.org/article/10.3389/fneur.2018.00827/full |
| work_keys_str_mv | AT runhuazhang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT runhuazhang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT runhuazhang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT runhuazhang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT gaifenliu acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT gaifenliu acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT gaifenliu acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT gaifenliu acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjiang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjiang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjiang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjiang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT gangli acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yuesongpan acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yuesongpan acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yuesongpan acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yuesongpan acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yilongwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yilongwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yilongwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yilongwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT zaihuawei acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT jingwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjunwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjunwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjunwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality AT yongjunwang acuteeffectsofparticulateairpollutiononischemicstrokeandhemorrhagicstrokemortality |