A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones

A New and Efficient Method for the Synthesis of 3,4-Disubstituted Pyrrolidine-2,5-diones

A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined.

Bibliographic Details
Main Authors:	Rositca D. Nikolova, Nevena I. Petkova, Eleonora D. Ilieva
Format:	Article
Language:	English
Published:	MDPI AG 2012-04-01
Series:	Molecules
Subjects:	pyrrolidine-2,5-dione pyrrolidine 3-substituted coumarins 2-oxo-2<em>Н</em>-1-benzopyrane Michael addition reaction rearrangement Nef reaction
Online Access:	http://www.mdpi.com/1420-3049/17/5/4936

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