The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease
Neurocognitive decline is one of the foremost dire issues in medicine today. The mechanisms by which dementia pathogenesis ensues are complicated and multifactorial, particularly in the case of Alzheimer’s disease (AD). One irrefutable, yet unexplained factor is the gender disparity in AD, in which...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1395825/full |
| _version_ | 1797203076231200768 |
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| author | Alison Warren |
| author_facet | Alison Warren |
| author_sort | Alison Warren |
| collection | DOAJ |
| description | Neurocognitive decline is one of the foremost dire issues in medicine today. The mechanisms by which dementia pathogenesis ensues are complicated and multifactorial, particularly in the case of Alzheimer’s disease (AD). One irrefutable, yet unexplained factor is the gender disparity in AD, in which women are disproportionately affected by AD, both in the rate and severity of the disease. Examining the multifaceted contributing causes along with unique gender dynamics in modifiable risk factors, such as diet, may lend some insight into why this disparity exists and potential paths forward. The aim of this brief narrative review is to summarize the current literature of gender differences in dietary habits and how they may relate to neuroinflammatory states that contribute to AD pathogenesis. As such, the interplay between diet, hormones, and inflammation will be discussed, along with potential interventions to inform care practices. |
| first_indexed | 2024-04-24T08:13:35Z |
| format | Article |
| id | doaj.art-192b7de41b97465f80380b4d42ae45bf |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-24T08:13:35Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-192b7de41b97465f80380b4d42ae45bf2024-04-17T04:34:34ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652024-04-011610.3389/fnagi.2024.13958251395825The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s diseaseAlison WarrenNeurocognitive decline is one of the foremost dire issues in medicine today. The mechanisms by which dementia pathogenesis ensues are complicated and multifactorial, particularly in the case of Alzheimer’s disease (AD). One irrefutable, yet unexplained factor is the gender disparity in AD, in which women are disproportionately affected by AD, both in the rate and severity of the disease. Examining the multifaceted contributing causes along with unique gender dynamics in modifiable risk factors, such as diet, may lend some insight into why this disparity exists and potential paths forward. The aim of this brief narrative review is to summarize the current literature of gender differences in dietary habits and how they may relate to neuroinflammatory states that contribute to AD pathogenesis. As such, the interplay between diet, hormones, and inflammation will be discussed, along with potential interventions to inform care practices.https://www.frontiersin.org/articles/10.3389/fnagi.2024.1395825/fullAlzheimer’s diseasedementiagendersexdietMediterranean diet |
| spellingShingle | Alison Warren The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease Frontiers in Aging Neuroscience Alzheimer’s disease dementia gender sex diet Mediterranean diet |
| title | The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease |
| title_full | The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease |
| title_fullStr | The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease |
| title_full_unstemmed | The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease |
| title_short | The relationship between gender differences in dietary habits, neuroinflammation, and Alzheimer’s disease |
| title_sort | relationship between gender differences in dietary habits neuroinflammation and alzheimer s disease |
| topic | Alzheimer’s disease dementia gender sex diet Mediterranean diet |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1395825/full |
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