Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak
Human mpox is a zoonotic disease, caused by the mpox virus (MPXV), that can spread either between animals and humans or humans and humans. In 1970 the first human case of mpox was reported in Zaire, Democratic Republic of the Congo (DRC). Other notable human mpox outbreaks in non-endemic countries w...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2024-01-01
|
| Series: | Romanian Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/rrlm-2024-0005 |
| _version_ | 1797323371333025792 |
|---|---|
| author | Goia Aneta-Rada Muntean Delia Musta Virgil Herlo Alexandra Vulpie Silvana Izmendi Oana Jumanca Romanita Licker Monica |
| author_facet | Goia Aneta-Rada Muntean Delia Musta Virgil Herlo Alexandra Vulpie Silvana Izmendi Oana Jumanca Romanita Licker Monica |
| author_sort | Goia Aneta-Rada |
| collection | DOAJ |
| description | Human mpox is a zoonotic disease, caused by the mpox virus (MPXV), that can spread either between animals and humans or humans and humans. In 1970 the first human case of mpox was reported in Zaire, Democratic Republic of the Congo (DRC). Other notable human mpox outbreaks in non-endemic countries were identified in June 2003 in the United States, in July 2021 in Dallas (USA), and the most recent one in May 2022 in Europe in the United Kingdom (UK). During the 2022 outbreak, sexual intercourse was observed to be the most prevalent transmission method, although other means should not be ignored, such as the involvement of respiratory droplets, exposure to surfaces and skin suspected of contamination. In the context of the current mpox outbreak, we consider it important and necessary to correctly identify the virus, use the proper laboratory testing for a correct diagnosis of mpox, understand the means of prophylaxis, and apply the correct treatment, highlighting these facts being the aim of this study. |
| first_indexed | 2024-03-08T05:27:42Z |
| format | Article |
| id | doaj.art-192c7e89b5364c2d84f100ff0903bc8c |
| institution | Directory Open Access Journal |
| issn | 2284-5623 |
| language | English |
| last_indexed | 2024-03-08T05:27:42Z |
| publishDate | 2024-01-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj.art-192c7e89b5364c2d84f100ff0903bc8c2024-02-06T09:10:18ZengSciendoRomanian Journal of Laboratory Medicine2284-56232024-01-0132110111010.2478/rrlm-2024-0005Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreakGoia Aneta-Rada0Muntean Delia1Musta Virgil2Herlo Alexandra3Vulpie Silvana4Izmendi Oana5Jumanca Romanita6Licker Monica71Doctoral School, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania2Department of Microbiology, Multidisciplinary Research Center on Antimicrobial Resistance, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania4Department XIII, Discipline of Infectious Diseases, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania4Department XIII, Discipline of Infectious Diseases, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania1Doctoral School, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania1Doctoral School, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania6Romanian and Foreign Languages Department, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania2Department of Microbiology, Multidisciplinary Research Center on Antimicrobial Resistance, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, RomaniaHuman mpox is a zoonotic disease, caused by the mpox virus (MPXV), that can spread either between animals and humans or humans and humans. In 1970 the first human case of mpox was reported in Zaire, Democratic Republic of the Congo (DRC). Other notable human mpox outbreaks in non-endemic countries were identified in June 2003 in the United States, in July 2021 in Dallas (USA), and the most recent one in May 2022 in Europe in the United Kingdom (UK). During the 2022 outbreak, sexual intercourse was observed to be the most prevalent transmission method, although other means should not be ignored, such as the involvement of respiratory droplets, exposure to surfaces and skin suspected of contamination. In the context of the current mpox outbreak, we consider it important and necessary to correctly identify the virus, use the proper laboratory testing for a correct diagnosis of mpox, understand the means of prophylaxis, and apply the correct treatment, highlighting these facts being the aim of this study.https://doi.org/10.2478/rrlm-2024-0005mpoxorthopox virusdiagnosislaboratory-based diagnosistreatment |
| spellingShingle | Goia Aneta-Rada Muntean Delia Musta Virgil Herlo Alexandra Vulpie Silvana Izmendi Oana Jumanca Romanita Licker Monica Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak Romanian Journal of Laboratory Medicine mpox orthopox virus diagnosis laboratory-based diagnosis treatment |
| title | Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak |
| title_full | Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak |
| title_fullStr | Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak |
| title_full_unstemmed | Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak |
| title_short | Understanding the pathogenesis, clinical, laboratory diagnosis and treatment of the recent monkeypox virus outbreak |
| title_sort | understanding the pathogenesis clinical laboratory diagnosis and treatment of the recent monkeypox virus outbreak |
| topic | mpox orthopox virus diagnosis laboratory-based diagnosis treatment |
| url | https://doi.org/10.2478/rrlm-2024-0005 |
| work_keys_str_mv | AT goiaanetarada understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT munteandelia understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT mustavirgil understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT herloalexandra understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT vulpiesilvana understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT izmendioana understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT jumancaromanita understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak AT lickermonica understandingthepathogenesisclinicallaboratorydiagnosisandtreatmentoftherecentmonkeypoxvirusoutbreak |