Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode
Background and purpose: Sensitive analytical determination of folic acid is important in clinical laboratories due to its versatile biological functions. Experimental approach: A simple folic acid sensor was successfully fabricated based on two-dimensional transition metal dichalcogenide MoS2 modif...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2023-07-01
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| Series: | ADMET and DMPK |
| Subjects: | |
| Online Access: | https://pub.iapchem.org/ojs/index.php/admet/article/view/1823 |
| _version_ | 1797666890016882688 |
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| author | Hadi Soltani Nejad Fariba Garkani Nejad Hadi Beitollahi |
| author_facet | Hadi Soltani Nejad Fariba Garkani Nejad Hadi Beitollahi |
| author_sort | Hadi Soltani Nejad |
| collection | DOAJ |
| description |
Background and purpose: Sensitive analytical determination of folic acid is important in clinical laboratories due to its versatile biological functions. Experimental approach: A simple folic acid sensor was successfully fabricated based on two-dimensional transition metal dichalcogenide MoS2 modified carbon ionic liquid paste electrode (MoS2-CILPE). The electrochemical properties of the fabricated electrode were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronoamperometry. Key results: The fabricated sensor displayed excellent electroactivity towards folic acid using CV. Under optimal conditions (0.1 M PBS (pH 7.0)), the DPV oxidation peak current was proportional to folic acid concentration in the range from 5.0 μM to 100.0 μM with an estimated limit of detection of 1.0 µM and limit of quantification of 5.0 µM. Conclusion: The ability of the sensor for routine analyses was demonstrated by the detection of folic acid present in folic acid tablets and urine samples with appreciable recovery values.
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| first_indexed | 2024-03-11T20:05:06Z |
| format | Article |
| id | doaj.art-193091c85ac94d749568640a86414587 |
| institution | Directory Open Access Journal |
| issn | 1848-7718 |
| language | English |
| last_indexed | 2024-03-11T20:05:06Z |
| publishDate | 2023-07-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | ADMET and DMPK |
| spelling | doaj.art-193091c85ac94d749568640a864145872023-10-03T23:13:08ZengInternational Association of Physical Chemists (IAPC)ADMET and DMPK1848-77182023-07-0111310.5599/admet.1823Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrodeHadi Soltani Nejad0Fariba Garkani Nejad1Hadi Beitollahi2Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman 7631818356, IranEnvironment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman 7631818356, IranEnvironment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran Background and purpose: Sensitive analytical determination of folic acid is important in clinical laboratories due to its versatile biological functions. Experimental approach: A simple folic acid sensor was successfully fabricated based on two-dimensional transition metal dichalcogenide MoS2 modified carbon ionic liquid paste electrode (MoS2-CILPE). The electrochemical properties of the fabricated electrode were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronoamperometry. Key results: The fabricated sensor displayed excellent electroactivity towards folic acid using CV. Under optimal conditions (0.1 M PBS (pH 7.0)), the DPV oxidation peak current was proportional to folic acid concentration in the range from 5.0 μM to 100.0 μM with an estimated limit of detection of 1.0 µM and limit of quantification of 5.0 µM. Conclusion: The ability of the sensor for routine analyses was demonstrated by the detection of folic acid present in folic acid tablets and urine samples with appreciable recovery values. https://pub.iapchem.org/ojs/index.php/admet/article/view/1823vitamin Btransition metal dichalcogenideselectrocatalysis |
| spellingShingle | Hadi Soltani Nejad Fariba Garkani Nejad Hadi Beitollahi Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode ADMET and DMPK vitamin B transition metal dichalcogenides electrocatalysis |
| title | Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode |
| title_full | Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode |
| title_fullStr | Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode |
| title_full_unstemmed | Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode |
| title_short | Development of a highly sensitive voltammetric sensor for the detection of folic acid by using MoS2 and ionic liquid-modified carbon paste electrode |
| title_sort | development of a highly sensitive voltammetric sensor for the detection of folic acid by using mos2 and ionic liquid modified carbon paste electrode |
| topic | vitamin B transition metal dichalcogenides electrocatalysis |
| url | https://pub.iapchem.org/ojs/index.php/admet/article/view/1823 |
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