Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study
Introduction: Recent decades show a considerable increase in fungal infections, hence can lead to fungal sinusitis. Immunosuppression, post organ transplant, diabetes mellitus, and Human Immunodeficiency Virus (HIV) infection have led to a rise in the incidence of fungal infections. Recent advan...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2023-01-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
| Subjects: | |
| Online Access: | https://ijars.net/article_fulltext.aspx?issn=0973-709x&year=2023&month=January&volume=12&issue=1&page=RO08%20-%20RO11&id=2859 |
| _version_ | 1811166502779355136 |
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| author | AM Anand Rintu George Elamparidhi Padmanaban Umamageshwari Amirthalingam |
| author_facet | AM Anand Rintu George Elamparidhi Padmanaban Umamageshwari Amirthalingam |
| author_sort | AM Anand |
| collection | DOAJ |
| description | Introduction: Recent decades show a considerable increase
in fungal infections, hence can lead to fungal sinusitis.
Immunosuppression, post organ transplant, diabetes mellitus,
and Human Immunodeficiency Virus (HIV) infection have led to
a rise in the incidence of fungal infections. Recent advances
in nasal endoscopy, Computed Tomography (CT), and
Histopathological Examination (HPE) Techniques have led to
better detection of fungal aetiology.
Aim: To determine the most significant CT findings in fungal
sinusitis or combination of findings in comparison to HPE.
Materials and Methods: This retrospective case-control
study was done at Sri Manakula Vinayagar Medical College
and Hospital, Puducherry from January 2017 to December
2020. Total number of patients were 90. Total 50 cases of
fungal sinusitis confirmed with histopathological confirmation
and available non contrast CT Paranasal Sinus (PNS) images
where time interval between CT and Functional Endoscopic
Sinus Surgery (FESS) not exceeding ten days were included.
The control group had 40 patients with chronic sinusitis with
HPE negative results. CT PNS were performed on PHILIPS
16 slice scanner without contrast administration. Data was
entered into Microsoft excel and analysed using Statistical
Package for the Social Sciences (SPSS) 22.0 version
software.
Results: Mean age of the cases (fungal sinusitis) were 46.7±17
years and 39±13.1 years of controls. Of the total 90 subjects,
heterogeneous mucosal thickening was seen in 41 (45.6%),
intrasinus hyperattenuation in 36 (40%), bone sclerosis in
44 (48.9%), bone erosion in 36 (40%), sinus expansion in
23 (25.6%) subjects. Fungal sinusitis patients had more
proportion of these findings when compared to control group
and hence p-value was significant.
Conclusion: The CT diagnostic features of the fungal sinusitis are
heterogeneous mucosal thickening, intrasinus hyperattenuation,
bone sclerosis, bone erosion and sinus expansion which were
significant. These findings help to differentiate fungal sinusitis
from non fungal sinusitis. |
| first_indexed | 2024-04-10T15:54:37Z |
| format | Article |
| id | doaj.art-19333a942f784fae9b8fb9bdd98f9258 |
| institution | Directory Open Access Journal |
| issn | 2277-8543 2455-6874 |
| language | English |
| last_indexed | 2024-04-10T15:54:37Z |
| publishDate | 2023-01-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | International Journal of Anatomy Radiology and Surgery |
| spelling | doaj.art-19333a942f784fae9b8fb9bdd98f92582023-02-10T15:49:07ZengJCDR Research and Publications Pvt. Ltd.International Journal of Anatomy Radiology and Surgery2277-85432455-68742023-01-01121 RO08RO1110.7860/IJARS/2023/55429.2859Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control StudyAM Anand0 Rintu George1Elamparidhi Padmanaban2Umamageshwari Amirthalingam3Associate Professor, Department of Radiodiagnosis, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.Senior Resident, Department of Radiodiagnosis, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India Associate Professor, Department of Radiodiagnosis, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India Professor, Department of Radiodiagnosis, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, India.Introduction: Recent decades show a considerable increase in fungal infections, hence can lead to fungal sinusitis. Immunosuppression, post organ transplant, diabetes mellitus, and Human Immunodeficiency Virus (HIV) infection have led to a rise in the incidence of fungal infections. Recent advances in nasal endoscopy, Computed Tomography (CT), and Histopathological Examination (HPE) Techniques have led to better detection of fungal aetiology. Aim: To determine the most significant CT findings in fungal sinusitis or combination of findings in comparison to HPE. Materials and Methods: This retrospective case-control study was done at Sri Manakula Vinayagar Medical College and Hospital, Puducherry from January 2017 to December 2020. Total number of patients were 90. Total 50 cases of fungal sinusitis confirmed with histopathological confirmation and available non contrast CT Paranasal Sinus (PNS) images where time interval between CT and Functional Endoscopic Sinus Surgery (FESS) not exceeding ten days were included. The control group had 40 patients with chronic sinusitis with HPE negative results. CT PNS were performed on PHILIPS 16 slice scanner without contrast administration. Data was entered into Microsoft excel and analysed using Statistical Package for the Social Sciences (SPSS) 22.0 version software. Results: Mean age of the cases (fungal sinusitis) were 46.7±17 years and 39±13.1 years of controls. Of the total 90 subjects, heterogeneous mucosal thickening was seen in 41 (45.6%), intrasinus hyperattenuation in 36 (40%), bone sclerosis in 44 (48.9%), bone erosion in 36 (40%), sinus expansion in 23 (25.6%) subjects. Fungal sinusitis patients had more proportion of these findings when compared to control group and hence p-value was significant. Conclusion: The CT diagnostic features of the fungal sinusitis are heterogeneous mucosal thickening, intrasinus hyperattenuation, bone sclerosis, bone erosion and sinus expansion which were significant. These findings help to differentiate fungal sinusitis from non fungal sinusitis.https://ijars.net/article_fulltext.aspx?issn=0973-709x&year=2023&month=January&volume=12&issue=1&page=RO08%20-%20RO11&id=2859bone erosionbone sclerosisintrasinus hyperattenuationparanasal sinusessinus expansion |
| spellingShingle | AM Anand Rintu George Elamparidhi Padmanaban Umamageshwari Amirthalingam Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study International Journal of Anatomy Radiology and Surgery bone erosion bone sclerosis intrasinus hyperattenuation paranasal sinuses sinus expansion |
| title | Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study |
| title_full | Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study |
| title_fullStr | Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study |
| title_full_unstemmed | Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study |
| title_short | Diagnostic Accuracy of Computed Tomography by Fungal Sinusitis: A Case-control Study |
| title_sort | diagnostic accuracy of computed tomography by fungal sinusitis a case control study |
| topic | bone erosion bone sclerosis intrasinus hyperattenuation paranasal sinuses sinus expansion |
| url | https://ijars.net/article_fulltext.aspx?issn=0973-709x&year=2023&month=January&volume=12&issue=1&page=RO08%20-%20RO11&id=2859 |
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