Design, synthesis and in silico molecular docking evaluation of novel 1,2,3-triazole derivatives as potent antimicrobial agents

Design, synthesis and in silico molecular docking evaluation of novel 1,2,3-triazole derivatives as potent antimicrobial agents

Chalcone and triazole scaffolds have demonstrated a crucial role in the advancement of science and technology. Due to their significance, research has proceeded on the design and development of novel benzooxepine connected to 1,2,3-triazolyl chalcone structures. The new chalcone derivatives produced...

Full description

Bibliographic Details
Main Authors:	Sudhakar Reddy Baddam, Mahesh Kumar Avula, Raghunadh Akula, Venkateswara Rao Battula, Sudhakar Kalagara, Ravinder Buchikonda, Srinivas Ganta, Srinivasadesikan Venkatesan, Tejeswara Rao Allaka
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Series:	Heliyon
Subjects:	Benzooxepines Chalcones 1,2,3-Triazoles Biological evaluations Docking interactions ADMETlab2.0
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024038040

Similar Items

Design, synthesis and in silico docking techniques of new 1,2,3-triazolylpyrrolidines bearing chalcone derivatives: Discovery of potent antitubercular agents
by: Veera Sankara Pavan Kumar Gudapati, et al.
Published: (2024-01-01)

Synthesis of novel pyrazoline based bis (1,2,3-triazole) scaffolds via click chemistry
by: Kiran Kothuri, et al.
Published: (2017-01-01)

Synthesis of newer substituted chalcone linked 1,2,3-triazole analogs and evaluation of their cytotoxic activities
by: Raghavender Matta, et al.
Published: (2022-10-01)

Microwave-assisted synthesis of new pyrazole derivatives bearing 1,2,3-triazole scaffold as potential antimicrobial agents
by: Ashok Dongamanti, et al.
Published: (2017-01-01)

Synthesis, characterization, cytotoxic evaluation, and molecular docking studies of novel 1,2,3-triazole-based chalcones for potential anticancer applications
by: Venkateswarlu Banoji, et al.
Published: (2024-01-01)

Eugenol derivatives containing 1,2,3-triazole-chalcone hybrids for shikimate kinase inhibition
by: Bayu Ardiansah, et al.
Published: (2024-03-01)

Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents
by: Sai-Yang Zhang, et al.
Published: (2016-05-01)

Design and development of novel 1,2,3-triazole chalcone derivatives as potential anti-osteosarcoma agents via inhibition of PI3K/Akt/mTOR signalling pathway
by: Su Qing, et al.
Published: (2022-09-01)

Synthesis, Characterization and Antibacterial Activity of Some New of Novel 1,2,3-Triazole-Chalcone Derivatives from N-Acetyl-5H-Dibenzo [b,f] Azepine-5-Carboxamide
by: Ruaa Wassim Adam, et al.
Published: (2019-06-01)

New Chalcone–Triazole Hybrids with Promising Antimicrobial Activity in Multidrug Resistance Strains
by: Daniela Pereira, et al.
Published: (2022-11-01)

Synthesis, anticancer and antibacterial evaluation of novel (isopropylidene) uridine-[1,2,3]triazole hybrids
by: Ranjith kumar Thatipamula, et al.
Published: (2017-11-01)

5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles
by: Robby Vroemans, et al.
Published: (2020-04-01)

5-Methyl-N′-(5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbonyl)-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide
by: Gamal A. El-Hiti, et al.
Published: (2018-03-01)

New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity
by: Mohamed T-E Maghraby, et al.
Published: (2023-10-01)

Recent advances in chalcone-triazole hybrids as potential pharmacological agents
by: Akanksha Bhukal, et al.
Published: (2023-12-01)

Heterociclos 1,2,3-triazólicos: histórico, métodos de preparação, aplicações e atividades farmacológicas 1,2,3-triazolic heterocycles: history, preparations, applications and pharmacological activities
by: Júlio O. F. Melo, et al.
Published: (2006-06-01)

1-(4-Fluorophenyl)-5-methyl-N′-{1-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]ethylidene}-1H-1,2,3-triazole-4-carbohydrazide
by: Gamal A. El-Hiti, et al.
Published: (2019-02-01)

Recent Progress in Catalytic Synthesis of 1,2,3-Triazoles
by: Antonio De Nino, et al.
Published: (2021-09-01)

Synthesis methods of 1,2,3-/1,2,4-triazoles: A review
by: Jinlian Dai, et al.
Published: (2022-09-01)

Synthesis and Antifungal Activity of Benzamidine Derivatives Carrying 1,2,3-Triazole Moieties
by: Guangyou Chen, et al.
Published: (2014-05-01)

Synthesis of new 1H-1,2,3-triazole-1,4-naphthoquinones
by: Wagner O. Valença, et al.
Published: (2012-06-01)

Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker
by: Iwona E. Głowacka, et al.
Published: (2015-10-01)

Combination of 1,2,3-triazole and 1,2,4-triazole frameworks for new high-energy and low-sensitivity compounds
by: Wenjing Yao, et al.
Published: (2021-06-01)

(<i>E</i>)-1-(5-Methyl-1-(4-nitrophenyl)-1<i>H</i>-1,2,3-triazol-4-yl)-3-(naphthalen-2-yl)prop-2-en-1-one
by: Benson M. Kariuki, et al.
Published: (2022-10-01)

1,2,3-Triazoles as Amide-bond Surrogates in Peptidomimetics
by: Ibai E. Valverde, et al.
Published: (2013-04-01)

Synthesis and Antioxidant Properties of Novel 1,2,3-Triazole-Containing Nitrones
by: Dimitra Hadjipavlou-Litina, et al.
Published: (2022-12-01)

Design, Synthesis, and Antimicrobial Activities of 1,2,3-Triazole Glycoside Clickamers
by: Tamer El Malah, et al.
Published: (2020-02-01)

Study on the Fluorescent Activity of N2-Indolyl-1,2,3-triazole
by: You-Can Zhang, et al.
Published: (2017-09-01)

Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids
by: David Milićević, et al.
Published: (2020-06-01)

Syntheses and Applications of 1,2,3-Triazole-Fused Pyrazines and Pyridazines
by: Gavin R. Hoffman, et al.
Published: (2022-07-01)

1-(4-Nitrophenyl)-1<i>H</i>-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles
by: Tomas Opsomer, et al.
Published: (2021-12-01)

Design, synthesis and biological evaluation of novel substituted indazole-1,2,3-triazolyl-1,3,4-oxadiazoles: Antimicrobial activity evaluation and docking study
by: Ananda Kumar Dunga, et al.
Published: (2022-01-01)

Exploring the Effects of Various Polymeric Backbones on the Performance of a Hydroxyaromatic 1,2,3-Triazole Anion Sensor
by: Aikohi Ugboya, et al.
Published: (2020-05-01)

Design and synthesis of cabotegravir derivatives bearing 1,2,3-triazole and evaluation of anti-liver cancer activity
by: Huaxia Xie, et al.
Published: (2023-10-01)

Synthesis of β-triazolylenones via metal-free desulfonylative alkylation of N-tosyl-1,2,3-triazoles
by: Soumyaranjan Pati, et al.
Published: (2021-03-01)

CuAAC-Based Synthesis, Copper-Catalyzed Aldehyde-Forming Hydrolytic Fission and Antiproliferative Evaluation of Novel Ferrocenoylamino-Substituted Triazole-Tethered Quinine–Chalcone Hybrids
by: António Dembo, et al.
Published: (2024-01-01)

Differentiation between Isomeric 4,5-Functionalized 1,2,3-Thiadiazoles and 1,2,3-Triazoles by ESI-HRMS and IR Ion Spectroscopy
by: Dmitrii M. Mazur, et al.
Published: (2023-01-01)

Silver-Catalyzed Cascade Cyclization of Amino-<i>NH</i>-1,2,3-Triazoles with 2-Alkynylbenzaldehydes: An Access to Pentacyclic Fused Triazoles
by: Shuitao Zhang, et al.
Published: (2022-11-01)

1,2,3-Triazoles and their metal chelates with antimicrobial activity
by: Lozan Todorov, et al.
Published: (2023-08-01)

1-Anilino-5-methyl-1H-1,2,3-triazole-4-carbaldehyde
by: Anna C. Cunha, et al.
Published: (2016-01-01)