Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System
Several applications exist for a whole brain positron-emission tomography (PET) brain imager designed as a portable unit that can be worn on a patient’s head. Enabled by improvements in detector technology, a lightweight, high performance device would allow PET brain imaging in different environment...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-05-01
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| Series: | Sensors |
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| Online Access: | http://www.mdpi.com/1424-8220/17/5/1164 |
| _version_ | 1818007298351562752 |
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| author | Samantha Melroy Christopher Bauer Matthew McHugh Garret Carden Alexander Stolin Stan Majewski Julie Brefczynski-Lewis Thorsten Wuest |
| author_facet | Samantha Melroy Christopher Bauer Matthew McHugh Garret Carden Alexander Stolin Stan Majewski Julie Brefczynski-Lewis Thorsten Wuest |
| author_sort | Samantha Melroy |
| collection | DOAJ |
| description | Several applications exist for a whole brain positron-emission tomography (PET) brain imager designed as a portable unit that can be worn on a patient’s head. Enabled by improvements in detector technology, a lightweight, high performance device would allow PET brain imaging in different environments and during behavioral tasks. Such a wearable system that allows the subjects to move their heads and walk—the Ambulatory Microdose PET (AM-PET)—is currently under development. This imager will be helpful for testing subjects performing selected activities such as gestures, virtual reality activities and walking. The need for this type of lightweight mobile device has led to the construction of a proof of concept portable head-worn unit that uses twelve silicon photomultiplier (SiPM) PET module sensors built into a small ring which fits around the head. This paper is focused on the engineering design of mechanical support aspects of the AM-PET project, both of the current device as well as of the coming next-generation devices. The goal of this work is to optimize design of the scanner and its mechanics to improve comfort for the subject by reducing the effect of weight, and to enable diversification of its applications amongst different research activities. |
| first_indexed | 2024-04-14T05:14:16Z |
| format | Article |
| id | doaj.art-193731b3eea044fb93a287daebe30d18 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-14T05:14:16Z |
| publishDate | 2017-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-193731b3eea044fb93a287daebe30d182022-12-22T02:10:26ZengMDPI AGSensors1424-82202017-05-01175116410.3390/s17051164s17051164Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) SystemSamantha Melroy0Christopher Bauer1Matthew McHugh2Garret Carden3Alexander Stolin4Stan Majewski5Julie Brefczynski-Lewis6Thorsten Wuest7Industrial and Management Systems Engineering, West Virginia University, Morgantown, WV 26506, USAMontgomery-Downs Lab, Blanchette Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV 26506, USAMechanical and Aerospace Engineering, West Virginia University, Morgantown, WV 26506, USAIndustrial and Management Systems Engineering, West Virginia University, Morgantown, WV 26506, USADepartment of Radiology, Center for Advanced Imaging, West Virginia University, Morgantown, WV 26506, USADepartment of Radiology & Medical Imaging, University of Virginia, Charlottesville, VA 22903, USAPhysiology & Pharmacology & Blanchette Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV 26506, USAIndustrial and Management Systems Engineering, West Virginia University, Morgantown, WV 26506, USASeveral applications exist for a whole brain positron-emission tomography (PET) brain imager designed as a portable unit that can be worn on a patient’s head. Enabled by improvements in detector technology, a lightweight, high performance device would allow PET brain imaging in different environments and during behavioral tasks. Such a wearable system that allows the subjects to move their heads and walk—the Ambulatory Microdose PET (AM-PET)—is currently under development. This imager will be helpful for testing subjects performing selected activities such as gestures, virtual reality activities and walking. The need for this type of lightweight mobile device has led to the construction of a proof of concept portable head-worn unit that uses twelve silicon photomultiplier (SiPM) PET module sensors built into a small ring which fits around the head. This paper is focused on the engineering design of mechanical support aspects of the AM-PET project, both of the current device as well as of the coming next-generation devices. The goal of this work is to optimize design of the scanner and its mechanics to improve comfort for the subject by reducing the effect of weight, and to enable diversification of its applications amongst different research activities.http://www.mdpi.com/1424-8220/17/5/1164positron emission tomographybrainbrain disorderswearablemicrodosebrain injuriesstrokedementiasautism |
| spellingShingle | Samantha Melroy Christopher Bauer Matthew McHugh Garret Carden Alexander Stolin Stan Majewski Julie Brefczynski-Lewis Thorsten Wuest Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System Sensors positron emission tomography brain brain disorders wearable microdose brain injuries stroke dementias autism |
| title | Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System |
| title_full | Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System |
| title_fullStr | Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System |
| title_full_unstemmed | Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System |
| title_short | Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System |
| title_sort | development and design of next generation head mounted ambulatory microdose positron emission tomography am pet system |
| topic | positron emission tomography brain brain disorders wearable microdose brain injuries stroke dementias autism |
| url | http://www.mdpi.com/1424-8220/17/5/1164 |
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