Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications

Natural hydrogels are one of the most promising biomaterials for tissue engineering applications, due to their biocompatibility, biodegradability, and extracellular matrix mimicking ability. To surpass the limitations of conventional fabrication techniques and to recapitulate the complex architectur...

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Main Authors: Kamil Elkhoury, Margaretha Morsink, Laura Sanchez-Gonzalez, Cyril Kahn, Ali Tamayol, Elmira Arab-Tehrany
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-11-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21001511
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author Kamil Elkhoury
Margaretha Morsink
Laura Sanchez-Gonzalez
Cyril Kahn
Ali Tamayol
Elmira Arab-Tehrany
author_facet Kamil Elkhoury
Margaretha Morsink
Laura Sanchez-Gonzalez
Cyril Kahn
Ali Tamayol
Elmira Arab-Tehrany
author_sort Kamil Elkhoury
collection DOAJ
description Natural hydrogels are one of the most promising biomaterials for tissue engineering applications, due to their biocompatibility, biodegradability, and extracellular matrix mimicking ability. To surpass the limitations of conventional fabrication techniques and to recapitulate the complex architecture of native tissue structure, natural hydrogels are being constructed using novel biofabrication strategies, such as textile techniques and three-dimensional bioprinting. These innovative techniques play an enormous role in the development of advanced scaffolds for various tissue engineering applications. The progress, advantages, and shortcomings of the emerging biofabrication techniques are highlighted in this review. Additionally, the novel applications of biofabricated natural hydrogels in cardiac, neural, and bone tissue engineering are discussed as well.
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spelling doaj.art-1938a114b01343b4a5a07f34e826a98f2024-04-16T21:09:54ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2021-11-0161139043923Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering ApplicationsKamil Elkhoury0Margaretha Morsink1Laura Sanchez-Gonzalez2Cyril Kahn3Ali Tamayol4Elmira Arab-Tehrany5LIBio, Université de Lorraine, Nancy, F-54000, FranceDepartment of Applied Stem Cell Technologies, TechMed Centre, University of Twente, Enschede, 7500AE, the NetherlandsLIBio, Université de Lorraine, Nancy, F-54000, FranceLIBio, Université de Lorraine, Nancy, F-54000, FranceDepartment of Biomedical Engineering, University of Connecticut, Farmington, CT, 06030, USA; Corresponding author.LIBio, Université de Lorraine, Nancy, F-54000, France; Corresponding author.Natural hydrogels are one of the most promising biomaterials for tissue engineering applications, due to their biocompatibility, biodegradability, and extracellular matrix mimicking ability. To surpass the limitations of conventional fabrication techniques and to recapitulate the complex architecture of native tissue structure, natural hydrogels are being constructed using novel biofabrication strategies, such as textile techniques and three-dimensional bioprinting. These innovative techniques play an enormous role in the development of advanced scaffolds for various tissue engineering applications. The progress, advantages, and shortcomings of the emerging biofabrication techniques are highlighted in this review. Additionally, the novel applications of biofabricated natural hydrogels in cardiac, neural, and bone tissue engineering are discussed as well.http://www.sciencedirect.com/science/article/pii/S2452199X21001511HydrogelMicrofabricationBioprintingTextilesTissue engineeringRegenerative medicine
spellingShingle Kamil Elkhoury
Margaretha Morsink
Laura Sanchez-Gonzalez
Cyril Kahn
Ali Tamayol
Elmira Arab-Tehrany
Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications
Bioactive Materials
Hydrogel
Microfabrication
Bioprinting
Textiles
Tissue engineering
Regenerative medicine
title Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications
title_full Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications
title_fullStr Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications
title_full_unstemmed Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications
title_short Biofabrication of natural hydrogels for cardiac, neural, and bone Tissue engineering Applications
title_sort biofabrication of natural hydrogels for cardiac neural and bone tissue engineering applications
topic Hydrogel
Microfabrication
Bioprinting
Textiles
Tissue engineering
Regenerative medicine
url http://www.sciencedirect.com/science/article/pii/S2452199X21001511
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