A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees

A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees

Abstract Background Although several genetic variants for autism spectrum disorder (ASD) have now been identified, these largely occur sporadically or are de novo. Much less progress has been made in identifying inherited variants, even though the disorder itself is familial in the majority of cases...

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Bibliographic Details
Main Authors: Marc Woodbury-Smith, Andrew D. Paterson, Irene O’Connor, Mehdi Zarrei, Ryan K. C. Yuen, Jennifer L Howe, Ann Thompson, Morgan Parlier, Bridget Fernandez, Joseph Piven, Stephen W. Scherer, Veronica Vieland, Peter Szatmari
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Autism spectrum disorder (ASD)
Genome-wide linkage
Posterior probability of linkage (PPL)
Family genetics
Extended pedigrees
Online Access:http://link.springer.com/article/10.1186/s11689-018-9238-9

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