Titanium Disk Surfaces Modulate Dental Implants Osseointegration
Titanium and titanium alloys are widely used as implant materials due to their excellent biocompatibility and mechanical properties. The aim of this work is to compare five different titanium layers in order to investigate which one had a greater osteoconductive power using Human Osteoblasts (HObs)...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2012-05-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/1721727X120100S209 |
| _version_ | 1818148358670254080 |
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| author | M. Lopez M. Andreasi Bassi L. Confalone S. Fanali V. Candotto F. Cura F. Carinci |
| author_facet | M. Lopez M. Andreasi Bassi L. Confalone S. Fanali V. Candotto F. Cura F. Carinci |
| author_sort | M. Lopez |
| collection | DOAJ |
| description | Titanium and titanium alloys are widely used as implant materials due to their excellent biocompatibility and mechanical properties. The aim of this work is to compare five different titanium layers in order to investigate which one had a greater osteoconductive power using Human Osteoblasts (HObs) culture for seven days on these surfaces. The expression levels of some bone-related genes (ALPL, COL1A1, COL3A1, SPP1, RUNX2 and SPARC) were analyzed using real time Reverse Transcription-Polymerase Chain Reaction (real time RT-PCR). Results obtained in this study demonstrate that titanium disks can lead to osteoblast differentiation and extracellular matrix deposition and mineralization by the activation of different osteoblast genes in relation to the specific type of surface treatment. |
| first_indexed | 2024-12-11T12:49:53Z |
| format | Article |
| id | doaj.art-193eb3bea35f405587c00b0da6383ae0 |
| institution | Directory Open Access Journal |
| issn | 1721-727X |
| language | English |
| last_indexed | 2024-12-11T12:49:53Z |
| publishDate | 2012-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | European Journal of Inflammation |
| spelling | doaj.art-193eb3bea35f405587c00b0da6383ae02022-12-22T01:06:42ZengSAGE PublishingEuropean Journal of Inflammation1721-727X2012-05-011010.1177/1721727X120100S209Titanium Disk Surfaces Modulate Dental Implants OsseointegrationM. Lopez0M. Andreasi Bassi1L. Confalone2S. Fanali3V. Candotto4F. Cura5F. Carinci6 Private practice, Rome, Italy Private practice, Rome, Italy Private practice, Rome, Italy Department of Oral Science, Nano and Biotechnology, University “G. D'Annunzio”, Chieti, Italy Department of D.M.C.C.C., Section of Maxillofacial and Plastic Surgery, University of Ferrara, Ferrara, Italy Department of histology, embryology and applied biology, University of Bologna, Bologna, Italy Department of D.M.C.C.C., Section of Maxillofacial and Plastic Surgery, University of Ferrara, Ferrara, ItalyTitanium and titanium alloys are widely used as implant materials due to their excellent biocompatibility and mechanical properties. The aim of this work is to compare five different titanium layers in order to investigate which one had a greater osteoconductive power using Human Osteoblasts (HObs) culture for seven days on these surfaces. The expression levels of some bone-related genes (ALPL, COL1A1, COL3A1, SPP1, RUNX2 and SPARC) were analyzed using real time Reverse Transcription-Polymerase Chain Reaction (real time RT-PCR). Results obtained in this study demonstrate that titanium disks can lead to osteoblast differentiation and extracellular matrix deposition and mineralization by the activation of different osteoblast genes in relation to the specific type of surface treatment.https://doi.org/10.1177/1721727X120100S209 |
| spellingShingle | M. Lopez M. Andreasi Bassi L. Confalone S. Fanali V. Candotto F. Cura F. Carinci Titanium Disk Surfaces Modulate Dental Implants Osseointegration European Journal of Inflammation |
| title | Titanium Disk Surfaces Modulate Dental Implants Osseointegration |
| title_full | Titanium Disk Surfaces Modulate Dental Implants Osseointegration |
| title_fullStr | Titanium Disk Surfaces Modulate Dental Implants Osseointegration |
| title_full_unstemmed | Titanium Disk Surfaces Modulate Dental Implants Osseointegration |
| title_short | Titanium Disk Surfaces Modulate Dental Implants Osseointegration |
| title_sort | titanium disk surfaces modulate dental implants osseointegration |
| url | https://doi.org/10.1177/1721727X120100S209 |
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