The Impact of Concomitant Proton Pump Inhibitors on Immunotherapy Efficacy among Patients with Urothelial Carcinoma: A Meta-Analysis

The Impact of Concomitant Proton Pump Inhibitors on Immunotherapy Efficacy among Patients with Urothelial Carcinoma: A Meta-Analysis

Background. Immune checkpoint inhibitors (ICIs) have recently represented a breakthrough in urothelial carcinoma (UC). Proton pump inhibitors (PPIs) are routinely used for extended time periods in UC patients, with these agents having potentially and frequently undervalued effects on ICIs efficacy....

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Bibliographic Details
Main Authors: Alessandro Rizzo, Matteo Santoni, Veronica Mollica, Angela Dalia Ricci, Concetta Calabrò, Antonio Cusmai, Gennaro Gadaleta-Caldarola, Gennaro Palmiotti, Francesco Massari
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Personalized Medicine
Subjects:
atezolizumab
durvalumab
immunotherapy
meta-analysis
nivolumab
pembrolizumab
Online Access:https://www.mdpi.com/2075-4426/12/5/842

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