Myelopoiesis during Solid Cancers and Strategies for Immunotherapy

Myelopoiesis during Solid Cancers and Strategies for Immunotherapy

Our understanding of the relationship between the immune system and cancers has undergone significant discovery recently. Immunotherapy with T cell therapies and checkpoint blockade has meaningfully changed the oncology landscape. While remarkable clinical advances in adaptive immunity are occurring...

Full description

Bibliographic Details
Main Authors:	Tyler J. Wildes, Bayli DiVita Dean, Catherine T. Flores
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Cells
Subjects:	myelopoiesis hematopoiesis hematopoietic stem and progenitor cell myeloid progenitor solid cancer malignancy
Online Access:	https://www.mdpi.com/2073-4409/10/5/968

Similar Items

Zebrafish: a convenient tool for myelopoiesis research
by: Yang-Xi Hu, et al.
Published: (2023-01-01)

PU.1 is required to restrain myelopoiesis during chronic inflammatory stress
by: James S. Chavez, et al.
Published: (2023-06-01)

Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
by: Yaeko Nakajima-Takagi, et al.
Published: (2023-06-01)

Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells
by: Maria Jassinskaja, et al.
Published: (2021-03-01)

Generation of Myeloid Cells in Cancer: The Spleen Matters
by: Chong Wu, et al.
Published: (2020-06-01)

Hematopoietic Progenitors and the Bone Marrow Niche Shape the Inflammatory Response and Contribute to Chronic Disease
by: Yangsong Xu, et al.
Published: (2022-02-01)

Hematologic dysfunction in cancer: Mechanisms, effects on antitumor immunity, and roles in disease progression
by: Viktoria Plackoska, et al.
Published: (2022-12-01)

Persistent Cutaneous <i>Leishmania major</i> Infection Promotes Infection-Adapted Myelopoiesis
by: Fabio Luiz Bandeira Ferreira, et al.
Published: (2022-02-01)

Protective effects against tumors and infection by interleukin-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors
by: Naoko Orii, et al.
Published: (2018-05-01)

Identification of Stromal Cells in Spleen Which Support Myelopoiesis
by: Hong Kiat Lim, et al.
Published: (2019-01-01)

Prenatal Origin of Pediatric Leukemia: Lessons From Hematopoietic Development
by: Anna Cazzola, et al.
Published: (2021-01-01)

Pilot Study on Mass Spectrometry–Based Analysis of the Proteome of CD34+CD123+ Progenitor Cells for the Identification of Potential Targets for Immunotherapy in Acute Myeloid Leukemia
by: Johannes R. Schmidt, et al.
Published: (2018-02-01)

Impaired Repopulating Ability of <i>Uhrf2</i><sup>−/−</sup> Hematopoietic Progenitor Cells in Mice
by: Takahiro Sano, et al.
Published: (2023-07-01)

Myelopoiesis of the Amphibian Xenopus laevis Is Segregated to the Bone Marrow, Away From Their Hematopoietic Peripheral Liver
by: Amulya Yaparla, et al.
Published: (2020-01-01)

Acute Myeloid Leukemia Cells Functionally Compromise Hematopoietic Stem/Progenitor Cells Inhibiting Normal Hematopoiesis Through the Release of Extracellular Vesicles
by: Stefania Trino, et al.
Published: (2022-03-01)

Hematopoietic Stem Cell (HSC)-Independent Progenitors Are Susceptible to Mll-Af9-Induced Leukemic Transformation
by: Cristiana Barone, et al.
Published: (2023-07-01)

Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice
by: Anas Alkhani, et al.
Published: (2023-01-01)

Single-cell RNA sequencing to track novel perspectives in HSC heterogeneity
by: Pan Zhang, et al.
Published: (2022-01-01)

Glucosamine Interferes With Myelopoiesis and Enhances the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells
by: Eric Chang-Yi Lin, et al.
Published: (2021-11-01)

Skeletal stem/progenitor cells provide the niche for extramedullary hematopoiesis in spleen
by: Helen C. O’Neill, et al.
Published: (2023-03-01)

Isolation of Murine Myeloid Progenitor Populations by CD34/CD150 Surface Markers
by: Leonid Olender, et al.
Published: (2022-01-01)

Cadmium exposure reprograms energy metabolism of hematopoietic stem cells to promote myelopoiesis at the expense of lymphopoiesis in mice
by: Yifan Zhao, et al.
Published: (2022-02-01)

Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells
by: Jianan Jiang, et al.
Published: (2022-02-01)

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis
by: Juliet R Girard, et al.
Published: (2021-10-01)

Induced pluripotent stem cell-derived hematopoietic stem and progenitor cells: potential, challenges, and future perspectives
by: Myoung Hee Han, et al.
Published: (2023-01-01)

Human Cytomegalovirus Infection Suppresses CD34<sup>+</sup> Progenitor Cell Engraftment in Humanized Mice
by: Lindsey B. Crawford, et al.
Published: (2020-04-01)

Hematopoietic Stem/Progenitor Cells and the Pathogenesis of HIV/AIDS
by: Tetsuo Tsukamoto
Published: (2020-02-01)

Multiple Myeloma-Derived Extracellular Vesicles Impair Normal Hematopoiesis by Acting on Hematopoietic Stem and Progenitor Cells
by: Ilaria Laurenzana, et al.
Published: (2021-12-01)

SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells
by: Mina N.F. Morcos, et al.
Published: (2017-06-01)

Insight into microRNAs’ involvement in hematopoiesis: current standing point of findings
by: Seyed Mahdi Nassiri, et al.
Published: (2023-10-01)

The Critical Role of Inflammation in the Pathogenesis and Progression of Myeloid Malignancies
by: Brianna M. Craver, et al.
Published: (2018-04-01)

E-Cigarette Exposure Decreases Bone Marrow Hematopoietic Progenitor Cells
by: Gajalakshmi Ramanathan, et al.
Published: (2020-08-01)

Advantages of adipose tissue stem cells over CD34+ mobilization to decrease hepatic fibrosis in Wistar rats
by: Marcela M. De Luna-Saldivar, et al.
Published: (2019-07-01)

Early Life Inflammation and the Developing Hematopoietic and Immune Systems: The Cochlea as a Sensitive Indicator of Disruption
by: Kelly S. Otsuka, et al.
Published: (2021-12-01)

Single-cell analysis at the protein level delineates intracellular signaling dynamic during hematopoiesis
by: Jinheng Wang, et al.
Published: (2021-09-01)

Altered Erythro-Myeloid Progenitor Cells Are Highly Expanded in Intensively Regenerating Hematopoiesis
by: Kateřina Faltusová, et al.
Published: (2020-02-01)

C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells
by: Branko Cirovic, et al.
Published: (2017-02-01)

The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer
by: Andrea J. Luker, et al.
Published: (2020-02-01)

Generation of CD34<sup>+</sup>CD43<sup>+</sup> Hematopoietic Progenitors to Induce Thymocytes from Human Pluripotent Stem Cells
by: Léa Flippe, et al.
Published: (2022-12-01)

Rapid and Reproducible Differentiation of Hematopoietic and T Cell Progenitors From Pluripotent Stem Cells
by: Léa Flippe, et al.
Published: (2020-10-01)