Myeloid-Derived Suppressor Cells in Sepsis

Myeloid-Derived Suppressor Cells in Sepsis

Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells characterized by their immunosuppressive functions. MDSCs expand during chronic and acute inflammatory conditions, the best described being cancer. Recent studies uncovered an important role of MDSCs in the pathogenesis of infectiou...

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Bibliographic Details
Main Authors: Irene T. Schrijver, Charlotte Théroude, Thierry Roger
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
sepsis
infectious disease
innate immunity
myeloid-derived suppressor cells
biomarker
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00327/full

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