Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran
<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">There are contradictory results regarding association between maternal HIV infection and neona...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2019-09-01
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| Series: | International Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://ijp.mums.ac.ir/article_13208_4cfc62222b045bcaca1b0cd32ef07b69.pdf |
| _version_ | 1798042233495093248 |
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| author | Nahid Najafi Elahe Amini Khadije Daneshjou Hossein Pesarakli Mahnaz Akbari |
| author_facet | Nahid Najafi Elahe Amini Khadije Daneshjou Hossein Pesarakli Mahnaz Akbari |
| author_sort | Nahid Najafi |
| collection | DOAJ |
| description | <strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">There are contradictory results regarding association between maternal HIV infection and neonatal adverse outcomes. Therefore, in this study the neonates born from HIV-positive mothers compared with HIV-negative mothers were assessed in Tehran, Iran.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">This retrospective case-control study was conducted on 50 infants born to an HIV-positive mother compared with 53 infants born to an HIV-negative mother as control group, during 8 years of a period from 2006-2015, admitted in Valiasr Hospital of Tehran. Data were gathered from medical records of patients.</span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">All children (n=53, 100%) in the case group were born through cesarean section; while 20.75% of the control group children were born by natural delivery (P=0.001). There was statistically significant difference between neonates born from HIV-positive mothers compared to HIV-negative mothers with respect to delivery method and gender (P<0.05). The mean weights (gr) were higher in the controls than the cases (3052.830±380.71 vs. 2731.80±575.90) (P=0.001). Also, a significantly increased Hemoglobin was observed in the controls (15.87±1.97 g/dL) compared to the cases (13.42±1.69 g/dL) (P=0.001). Liver functions test (LFTs)was significantly higher in case groups (P=0.005).</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">Based on the results,the mean weight and hemoglobin were lower in infants born from HIV-positive women compared with HIV-negative women. Also, LFT Disorder was higher in infants born from HIV-positive women compared with HIV-negative women. </span> |
| first_indexed | 2024-04-11T22:32:39Z |
| format | Article |
| id | doaj.art-1945471092d2459cbded7c70a54192b5 |
| institution | Directory Open Access Journal |
| issn | 2345-5047 2345-5055 |
| language | English |
| last_indexed | 2024-04-11T22:32:39Z |
| publishDate | 2019-09-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj.art-1945471092d2459cbded7c70a54192b52022-12-22T03:59:19ZengMashhad University of Medical SciencesInternational Journal of Pediatrics2345-50472345-50552019-09-0179100491005610.22038/ijp.2019.40474.342213208Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, IranNahid Najafi0Elahe Amini1Khadije Daneshjou2Hossein Pesarakli3Mahnaz Akbari4Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.NICU Division, Valiasr Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Pediatrics, School of Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Pediatrics, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.<strong><em><span style="font-family: Times New Roman;">Background</span></em></strong><br /> <span style="font-family: Times New Roman;">There are contradictory results regarding association between maternal HIV infection and neonatal adverse outcomes. Therefore, in this study the neonates born from HIV-positive mothers compared with HIV-negative mothers were assessed in Tehran, Iran.</span><br /> <strong><em><span style="font-family: Times New Roman;">Materials and Methods</span></em></strong><br /> <span style="font-family: Times New Roman;">This retrospective case-control study was conducted on 50 infants born to an HIV-positive mother compared with 53 infants born to an HIV-negative mother as control group, during 8 years of a period from 2006-2015, admitted in Valiasr Hospital of Tehran. Data were gathered from medical records of patients.</span><br /> <strong><em><span style="font-family: Times New Roman;">Results</span></em></strong><br /> <span style="font-family: Times New Roman;">All children (n=53, 100%) in the case group were born through cesarean section; while 20.75% of the control group children were born by natural delivery (P=0.001). There was statistically significant difference between neonates born from HIV-positive mothers compared to HIV-negative mothers with respect to delivery method and gender (P<0.05). The mean weights (gr) were higher in the controls than the cases (3052.830±380.71 vs. 2731.80±575.90) (P=0.001). Also, a significantly increased Hemoglobin was observed in the controls (15.87±1.97 g/dL) compared to the cases (13.42±1.69 g/dL) (P=0.001). Liver functions test (LFTs)was significantly higher in case groups (P=0.005).</span><br /> <strong><em><span style="font-family: Times New Roman;">Conclusion</span></em></strong><br /> <span style="font-family: Times New Roman;">Based on the results,the mean weight and hemoglobin were lower in infants born from HIV-positive women compared with HIV-negative women. Also, LFT Disorder was higher in infants born from HIV-positive women compared with HIV-negative women. </span>http://ijp.mums.ac.ir/article_13208_4cfc62222b045bcaca1b0cd32ef07b69.pdfAidsInfantHIVMother |
| spellingShingle | Nahid Najafi Elahe Amini Khadije Daneshjou Hossein Pesarakli Mahnaz Akbari Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran International Journal of Pediatrics Aids Infant HIV Mother |
| title | Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran |
| title_full | Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran |
| title_fullStr | Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran |
| title_full_unstemmed | Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran |
| title_short | Clinical Findings of Infants Born to an HIV-Positive Mother: A Hospital Based Case-Control Study in Tehran, Iran |
| title_sort | clinical findings of infants born to an hiv positive mother a hospital based case control study in tehran iran |
| topic | Aids Infant HIV Mother |
| url | http://ijp.mums.ac.ir/article_13208_4cfc62222b045bcaca1b0cd32ef07b69.pdf |
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