Design, synthesis and in vitro biological activities of coumarin linked 1,3,4-oxadiazole hybrids as potential multi-target directed anti-Alzheimer agents

Introduction: Alzheimer’s disease (AD) is one of the most common and prevalent forms of neurodegenerative diseases. Coumarin is a versatile scaffold that exhibits a wide range of biological properties including cholinesterase inhibitory activity and therefore is an important heterocyclic moiety to d...

Полное описание

Библиографические подробности
Главные авторы: Namy George, Bushra Al Sabahi, Majed AbuKhader, Khalid Al Balushi, Md. Jawaid Akhtar, Shah Alam Khan
Формат: Статья
Язык:English
Опубликовано: Elsevier 2022-06-01
Серии:Journal of King Saud University: Science
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Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1018364722001586