The Future of Targeted Therapy for Leiomyosarcoma

The Future of Targeted Therapy for Leiomyosarcoma

Leiomyosarcoma (LMS) is an aggressive subtype of soft tissue sarcoma that arises from smooth muscle cells, most commonly in the uterus and retroperitoneum. LMS is a heterogeneous disease with diverse clinical and molecular characteristics that have yet to be fully understood. Molecular profiling has...

Full description

Bibliographic Details
Main Authors:	Ryan A. Denu, Amanda M. Dann, Emily Z. Keung, Michael S. Nakazawa, Elise F. Nassif Haddad
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Series:	Cancers
Subjects:	leiomyosarcoma genomics transcriptomics immunotherapy precision oncology targeted therapy
Online Access:	https://www.mdpi.com/2072-6694/16/5/938

Similar Items

Targeting the Molecular and Immunologic Features of Leiomyosarcoma
by: Brandon M. Cope, et al.
Published: (2023-03-01)

Primary adrenal leiomyosarcoma
by: Andrew Waack, BS, et al.
Published: (2023-03-01)

Leiomyosarcoma, a rare smooth muscle cancer in the pancreas: An adjuvant radiotherapy treatment approach
by: Ali Taghizadeh Kermani, et al.
Published: (2023-06-01)

Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma
by: Yukari Nagao, et al.
Published: (2023-03-01)

Status of the Current Treatment Options and Potential Future Targets in Uterine Leiomyosarcoma: A Review
by: Hiroshi Asano, et al.
Published: (2022-02-01)

Molecular subtypes of leiomyosarcoma: Moving toward a consensus
by: Jessica Burns, et al.
Published: (2022-12-01)

Laryngeal Leiomyosarcoma
by: Burak ERTAŞ, et al.
Published: (2018-01-01)

Targeting Class I Histone Deacetylases in Human Uterine Leiomyosarcoma
by: Qiwei Yang, et al.
Published: (2022-11-01)

Diagnosis and treatment in a case of uterine leiomyosarcoma - case report and review of the literature
by: Monika Pająk, et al.
Published: (2023-08-01)

Misdiagnosis and mistreatment of uterine myxoid leiomyosarcoma: A case report and literature review
by: Ruiping Li, et al.
Published: (2023-07-01)

Association of chondroadherin with leiomyosarcoma
by: Sefik Gokce, et al.
Published: (2023-04-01)

Retrospective analysis of adjuvant treatment for localized, operable uterine leiomyosarcoma
by: Jomjit Chantharasamee, et al.
Published: (2022-08-01)

Posterior mediastinal epithelioid leiomyosarcoma: Case report and literature review
by: Cosmin Iacoban, DO, et al.
Published: (2022-03-01)

Cystic renal leiomyosarcoma : An aggressive tumour
by: M Raghavendran, et al.
Published: (2002-01-01)

Leiomyosarcoma presenting as unilateral painless testicular mass in a septuagenarian: a case report with review of the literature
by: Brijmohan Joshi, et al.
Published: (2022-10-01)

Gastric leiomyosarcoma mimicking splenomegaly
by: Samuel O C. Emedike, et al.
Published: (2001-01-01)

High grade leiomyosarcoma of the testes
by: Girish D. Bakhshi, et al.
Published: (2011-11-01)

When Vessels and Sarcomas Combine: A Review of the Inferior Vena Cava Leiomyosarcoma
by: João Martins Gama, et al.
Published: (2024-01-01)

Primary Leiomyosarcoma of Breast
by: Caren Dsouza1 , Shubha Rao2 , Erel Diaz3 , Supreeth4 , Gnaneshwari J5 , Manohar M6
Published: (2017-12-01)

Primary leiomyosarcoma with osteosarcomatous differentiation of the breast
by: Ekta Sethi, et al.
Published: (2024-02-01)

Primary Leiomyosarcoma of the Breast with Unusual Metastasis
by: Malek Bouhani, et al.
Published: (2019-12-01)

Renal Leiomyosarcoma, a Rare Presentation
by: Toukilnan Djiwa, et al.
Published: (2022-03-01)

The Future of Precision Oncology
by: Stuart L. Rulten, et al.
Published: (2023-08-01)

Epididymal leiomyosarcoma: Report of a rare case
by: Mansoureh Dehghani, et al.
Published: (2022-03-01)

A promising response of refractory uterine leiomyosarcoma to pembrolizumab and temozolomide combination therapy
by: Rebecca Lin, et al.
Published: (2024-02-01)

Emerging predictive biomarkers for novel therapeutics in peripheral T-cell and natural killer/T-cell lymphoma
by: Daniel Ren Yi Yap, et al.
Published: (2023-01-01)

Leiomyosarcoma of the axillary vein
by: Hossam Alslaim, et al.
Published: (2022-03-01)

Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients—A Position Paper from the National LeioMyoSarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN)
by: Bernd Kasper, et al.
Published: (2021-02-01)

Metastatic Pattern of Truncal and Extremity Leiomyosarcoma: Retrospective Analysis of Predictors, Outcomes, and Detection
by: Seth S. Tigchelaar, et al.
Published: (2022-02-01)

Case report: a grievous tale of a rare primary thyroid leiomyosarcoma
by: Wan Nabila Wan Mansor, et al.
Published: (2023-01-01)

Beyond Limits: A Case of Progressive Leiomyosarcoma of the Mandible
by: Mel Valerie Cruz Ordinario, et al.
Published: (2023-06-01)

A rare case of intracardiac metastasis of uterine leiomyosarcoma
by: Khadije Mohammadi, et al.
Published: (2022-10-01)

Uterine leiomyosarcoma in a dog: a case report
by: G. Serin, et al.
Published: (2010-08-01)

Leiomyosarcoma of the Maxilla: A Case Report and Literature Review
by: Mohammad Jafarian, et al.
Published: (2022-06-01)

Pancreatic leiomyosarcoma: a case report
by: M. P. Nikulin, et al.
Published: (2022-03-01)

A Rare Case of Pulmonary Leiomyosarcoma
by: Jialin He, et al.
Published: (2023-01-01)

Primary pleomorphic leiomyosarcoma of descending mesocolon
by: Suhaildeen Kajamohideen, et al.
Published: (2021-01-01)

Case Report of Suspected Rhabdomyolysis during Treatment with Trabectedin in a Patient with Metastatic Leiomyosarcoma
by: W. Lamm, et al.
Published: (2010-12-01)

A case of metastatic endobronchial tumor from uterine leiomyosarcoma
by: Manabu Ono, et al.
Published: (2022-01-01)

Identification of Genetic Alterations by Circulating Tumor DNA in Leiomyosarcoma: A Molecular Analysis of 73 Patients
by: Junaid Arshad, et al.
Published: (2020-05-01)