Tumor bioengineering using a transglutaminase crosslinked hydrogel.
Development of a physiologically relevant 3D model system for cancer research and drug development is a current challenge. We have adopted a 3D culture system based on a transglutaminase-crosslinked gelatin gel (Col-Tgel) to mimic the tumor 3D microenvironment. The system has several unique advantag...
Main Authors: | Josephine Y Fang, Shih-Jye Tan, Zhi Yang, Charisse Tayag, Bo Han |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4136878?pdf=render |
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