Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain
Three-dimensional (3D) gradient recalled echo (GRE) sequence with magnetization transfer (MT) can simultaneously image neuromelanin and magnetic susceptibility. However, the sequence requires long duration of MT saturation pulse and the effect of MT pulse on susceptibility values remains unclear. Th...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Science Press
2023-12-01
|
| Series: | Chinese Journal of Magnetic Resonance |
| Subjects: | |
| Online Access: | http://121.43.60.238/bpxzz/article/2023/1000-4556/1000-4556-40-4-385.shtml |
| _version_ | 1797401863822245888 |
|---|---|
| author | CHEN Mengying WU Yupeng PANG Qifan ZHONG Haodong LI Gaiying LI Jianqi |
| author_facet | CHEN Mengying WU Yupeng PANG Qifan ZHONG Haodong LI Gaiying LI Jianqi |
| author_sort | CHEN Mengying |
| collection | DOAJ |
| description | Three-dimensional (3D) gradient recalled echo (GRE) sequence with magnetization transfer (MT) can simultaneously image neuromelanin and magnetic susceptibility. However, the sequence requires long duration of MT saturation pulse and the effect of MT pulse on susceptibility values remains unclear. Therefore, this paper aims to shorten the MT pulse duration and evaluate the effect of MT pulse on susceptibility value. Results showed that 3D GRE sequence with 5 ms of MT pulse provided a saturation effect no less than that of 8 ms, 10 ms and 12 ms in highlighting neuromelanin, and yielded susceptibility values in the deep gray matter nuclei similar to sequence without MT pulse. In conclusion, short MT pulse provides a practical means to simultaneously image the neuromelanin and magnetic susceptibility. |
| first_indexed | 2024-03-09T02:16:32Z |
| format | Article |
| id | doaj.art-194beabefc7749e89f5dc7db1a747333 |
| institution | Directory Open Access Journal |
| issn | 1000-4556 |
| language | zho |
| last_indexed | 2024-03-09T02:16:32Z |
| publishDate | 2023-12-01 |
| publisher | Science Press |
| record_format | Article |
| series | Chinese Journal of Magnetic Resonance |
| spelling | doaj.art-194beabefc7749e89f5dc7db1a7473332023-12-07T02:37:42ZzhoScience PressChinese Journal of Magnetic Resonance1000-45562023-12-0140438539610.11938/cjmr20233062Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole BrainCHEN MengyingWU Yupeng0PANG Qifan1ZHONG Haodong2LI Gaiying3LI Jianqi4Shanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai 200062, ChinaShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai 200062, ChinaShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai 200062, ChinaShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai 200062, ChinaShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, Shanghai 200062, ChinaThree-dimensional (3D) gradient recalled echo (GRE) sequence with magnetization transfer (MT) can simultaneously image neuromelanin and magnetic susceptibility. However, the sequence requires long duration of MT saturation pulse and the effect of MT pulse on susceptibility values remains unclear. Therefore, this paper aims to shorten the MT pulse duration and evaluate the effect of MT pulse on susceptibility value. Results showed that 3D GRE sequence with 5 ms of MT pulse provided a saturation effect no less than that of 8 ms, 10 ms and 12 ms in highlighting neuromelanin, and yielded susceptibility values in the deep gray matter nuclei similar to sequence without MT pulse. In conclusion, short MT pulse provides a practical means to simultaneously image the neuromelanin and magnetic susceptibility.http://121.43.60.238/bpxzz/article/2023/1000-4556/1000-4556-40-4-385.shtmlneuromelanin-sensitive magnetic resonance imaging (nm-mri)magnetization transfer (mt)quantitative susceptibility mapping (qsm)deep gray matter nuclei |
| spellingShingle | CHEN Mengying WU Yupeng PANG Qifan ZHONG Haodong LI Gaiying LI Jianqi Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain Chinese Journal of Magnetic Resonance neuromelanin-sensitive magnetic resonance imaging (nm-mri) magnetization transfer (mt) quantitative susceptibility mapping (qsm) deep gray matter nuclei |
| title | Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain |
| title_full | Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain |
| title_fullStr | Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain |
| title_full_unstemmed | Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain |
| title_short | Simultaneously Neuromelanin-sensitive Imaging and Quantitative Susceptibility Mapping in the Whole Brain |
| title_sort | simultaneously neuromelanin sensitive imaging and quantitative susceptibility mapping in the whole brain |
| topic | neuromelanin-sensitive magnetic resonance imaging (nm-mri) magnetization transfer (mt) quantitative susceptibility mapping (qsm) deep gray matter nuclei |
| url | http://121.43.60.238/bpxzz/article/2023/1000-4556/1000-4556-40-4-385.shtml |
| work_keys_str_mv | AT chenmengying simultaneouslyneuromelaninsensitiveimagingandquantitativesusceptibilitymappinginthewholebrain AT wuyupeng simultaneouslyneuromelaninsensitiveimagingandquantitativesusceptibilitymappinginthewholebrain AT pangqifan simultaneouslyneuromelaninsensitiveimagingandquantitativesusceptibilitymappinginthewholebrain AT zhonghaodong simultaneouslyneuromelaninsensitiveimagingandquantitativesusceptibilitymappinginthewholebrain AT ligaiying simultaneouslyneuromelaninsensitiveimagingandquantitativesusceptibilitymappinginthewholebrain AT lijianqi simultaneouslyneuromelaninsensitiveimagingandquantitativesusceptibilitymappinginthewholebrain |