Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype
Sarcoidosis is a systemic disease histologically characterized by the presence of non-caseating granulomas. Granulomas can affect all structures of the body, giving heterogeneous manifestations and making the diagnosis of this disease a real challenge. We report the case of a 72-year-old woman who...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-05-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/9097 |
| _version_ | 1797800755147571200 |
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| author | Donia Chebbi Raida Ben Salah Faten Frikha Hela Fourati Mariem Ghribi Zeineb Mnif Zouhir Bahloul |
| author_facet | Donia Chebbi Raida Ben Salah Faten Frikha Hela Fourati Mariem Ghribi Zeineb Mnif Zouhir Bahloul |
| author_sort | Donia Chebbi |
| collection | DOAJ |
| description |
Sarcoidosis is a systemic disease histologically characterized by the presence of non-caseating granulomas. Granulomas can affect all structures of the body, giving heterogeneous manifestations and making the diagnosis of this disease a real challenge. We report the case of a 72-year-old woman who presented with two rare manifestations of sarcoidosis: an orbital and a pulmonary pseudotumor. The orbital tumor revealed the disease. Clinically, the patient had palpebral swelling. Orbital MRI showed an orbital pseudotumor hypointense on T1, and hyperintense on T2, heterogeneous and enhanced after gadolinium injection. The thoracic localization was asymptomatic, revealed by the chest Computed Tomography (CT) scan. Histological evidence of granuloma was obtained at both locations. The level of angiotensin-converting enzyme was high. All the other systemic granulomatous diseases were eliminated. We started a systemic corticotherapy with good clinical results.
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| first_indexed | 2024-03-13T04:40:03Z |
| format | Article |
| id | doaj.art-194fae6666344826a329a1a7f54cbcba |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-03-13T04:40:03Z |
| publishDate | 2023-05-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-194fae6666344826a329a1a7f54cbcba2023-06-19T06:21:07ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942023-05-0161310.18502/acta.v61i3.12743Systemic Sarcoidosis With a Pseudo-Tumoral PhenotypeDonia Chebbi0Raida Ben Salah1Faten Frikha2Hela Fourati3Mariem Ghribi4Zeineb Mnif5Zouhir Bahloul6Department of Internal Medicine, Hedi Chaker University Hospital, Medical School of Sfax, University of Sfax, Sfax, TunisiaDepartment of Internal Medicine, Hedi Chaker University Hospital, Medical School of Sfax, University of Sfax, Sfax, TunisiaDepartment of Internal Medicine, Hedi Chaker University Hospital, Medical School of Sfax, University of Sfax, Sfax, TunisiaDepartment of radiology, Hedi Chaker university hospital, SfaxDepartment of Internal Medicine, Hedi Chaker University Hospital, Medical School of Sfax, University of Sfax, Sfax, TunisiaDepartment of Internal Medicine, Hedi Chaker University Hospital, Medical School of Sfax, University of Sfax, Sfax, TunisiaDepartment of Internal Medicine, Hedi Chaker University Hospital, Medical School of Sfax, University of Sfax, Sfax, Tunisia Sarcoidosis is a systemic disease histologically characterized by the presence of non-caseating granulomas. Granulomas can affect all structures of the body, giving heterogeneous manifestations and making the diagnosis of this disease a real challenge. We report the case of a 72-year-old woman who presented with two rare manifestations of sarcoidosis: an orbital and a pulmonary pseudotumor. The orbital tumor revealed the disease. Clinically, the patient had palpebral swelling. Orbital MRI showed an orbital pseudotumor hypointense on T1, and hyperintense on T2, heterogeneous and enhanced after gadolinium injection. The thoracic localization was asymptomatic, revealed by the chest Computed Tomography (CT) scan. Histological evidence of granuloma was obtained at both locations. The level of angiotensin-converting enzyme was high. All the other systemic granulomatous diseases were eliminated. We started a systemic corticotherapy with good clinical results. https://acta.tums.ac.ir/index.php/acta/article/view/9097Systemic sarcoidosisorbital tumorpulmonary pseudotumorAngiotensin converting enzymecorticotherapy |
| spellingShingle | Donia Chebbi Raida Ben Salah Faten Frikha Hela Fourati Mariem Ghribi Zeineb Mnif Zouhir Bahloul Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype Acta Medica Iranica Systemic sarcoidosis orbital tumor pulmonary pseudotumor Angiotensin converting enzyme corticotherapy |
| title | Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype |
| title_full | Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype |
| title_fullStr | Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype |
| title_full_unstemmed | Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype |
| title_short | Systemic Sarcoidosis With a Pseudo-Tumoral Phenotype |
| title_sort | systemic sarcoidosis with a pseudo tumoral phenotype |
| topic | Systemic sarcoidosis orbital tumor pulmonary pseudotumor Angiotensin converting enzyme corticotherapy |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/9097 |
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