ADENOVIRUS INFECTION AS ONE OF POSSIBLE CAUSES OF FATTY HEPATOSIS IN ONE DAY–OLD CHICKENS

Aim. To investigate the role of adenovirus infection in the development of fatty liver disease in one day-old chicks. Methods. The condition of the internal organs of poultry assessed by autopsy, the amount of vitamin A in the liver of chickens determined photocolorimetry. Microscopic evaluation of...

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Bibliographic Details
Main Authors: О. О. Нечипуренко, Д. В. Древаль, Д. Д. Провозін, І. О. Собко
Format: Article
Language:English
Published: Odessa I. I. Mechnikov National University 2016-12-01
Series:Mìkrobìologìâ ì Bìotehnologìâ
Subjects:
Online Access:http://mbt.onu.edu.ua/article/view/86787
Description
Summary:Aim. To investigate the role of adenovirus infection in the development of fatty liver disease in one day-old chicks. Methods. The condition of the internal organs of poultry assessed by autopsy, the amount of vitamin A in the liver of chickens determined photocolorimetry. Microscopic evaluation of changes in the liver and the presence of adenovirus infection were determined by histologic examination. The staining of the tissues was performed by a standard technique with hematoxylin and eosin solutions. Results. In the liver, of 23-th day-old chicks were revealed fatty degeneration of hepatocytes. The amount of vitamin A in the liver of investigated samples varied in the range of 10.0–20.4 mg / g. The presence of a bacterial infection in breeder explains the fact that from 22% of the investigated day-old chicks was isolated E. coli. According to the results of the histological analysis of the liver and kidneys breeder hens were detected basophilic intranuclear inclusion bodies, which indicate the presence of adenovirus infection and its possible transovarial transmission. Conclusion. Infection of breeder by adenovirus, despite the balanced diet with vitamins, causing fatty degeneration of hepatocytes and decrease the concentration of vitamin A in the liver of one day-old chicks in 1.4–2.8 times compared with the norm.
ISSN:2076-0558
2307-4663