PPARA genetic variants increase the risk for cardiac pumping function reductions following acute high‐altitude exposure: A self‐controlled study

PPARA genetic variants increase the risk for cardiac pumping function reductions following acute high‐altitude exposure: A self‐controlled study

Abstract Background Left cardiac pumping function determines the compensatory capacity of the cardiovascular system following acute high‐altitude exposure. Variations in cardiac output (CO) at high altitude are inconsistent between individuals, and genetic susceptibility may play a crucial role. We...

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Bibliographic Details
Main Authors: Jie Yang, Chuan Liu, Zhang Jihang, Jie Yu, Limeng Dai, Xiaohan Ding, Youzhu Qiu, Sanjiu Yu, Yuanqi Yang, Yuzhang Wu, Lan Huang
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
cardiac function
genotype–phenotype correlation
haplotypes
high altitude
PPARA
Online Access:https://doi.org/10.1002/mgg3.919

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