Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities
This article tries to demonstrate by new pathological findings (with the use of immunohistochemical technique and confocal laser microscopy) that chronic chagasic cardiomyopathy is a result of multiple factors involving myocarditis, immunodepression, severe fibrosis and microvessels dilatation and t...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
1999-09-01
|
| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700044 |
| _version_ | 1797756614976995328 |
|---|---|
| author | Maria de Lourdes Higuchi |
| author_facet | Maria de Lourdes Higuchi |
| author_sort | Maria de Lourdes Higuchi |
| collection | DOAJ |
| description | This article tries to demonstrate by new pathological findings (with the use of immunohistochemical technique and confocal laser microscopy) that chronic chagasic cardiomyopathy is a result of multiple factors involving myocarditis, immunodepression, severe fibrosis and microvessels dilatation and that all of these alterations are probably directly related with the presence of Trypanosoma cruzi parasites in the host associated with inadequate immunological response of the host. |
| first_indexed | 2024-03-12T18:03:11Z |
| format | Article |
| id | doaj.art-195349c1b08b4aaeacb458cd74db2466 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:03:11Z |
| publishDate | 1999-09-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-195349c1b08b4aaeacb458cd74db24662023-08-02T09:32:21ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601999-09-019426326710.1590/S0074-02761999000700044Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalitiesMaria de Lourdes HiguchiThis article tries to demonstrate by new pathological findings (with the use of immunohistochemical technique and confocal laser microscopy) that chronic chagasic cardiomyopathy is a result of multiple factors involving myocarditis, immunodepression, severe fibrosis and microvessels dilatation and that all of these alterations are probably directly related with the presence of Trypanosoma cruzi parasites in the host associated with inadequate immunological response of the host.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700044Chagas diseasemyocarditisTrypanosoma cruziimmunodepression |
| spellingShingle | Maria de Lourdes Higuchi Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities Memorias do Instituto Oswaldo Cruz Chagas disease myocarditis Trypanosoma cruzi immunodepression |
| title | Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities |
| title_full | Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities |
| title_fullStr | Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities |
| title_full_unstemmed | Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities |
| title_short | Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities |
| title_sort | human chronic chagasic cardiopathy participation of parasite antigens subsets of lymphocytes cytokines and microvascular abnormalities |
| topic | Chagas disease myocarditis Trypanosoma cruzi immunodepression |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761999000700044 |
| work_keys_str_mv | AT mariadelourdeshiguchi humanchronicchagasiccardiopathyparticipationofparasiteantigenssubsetsoflymphocytescytokinesandmicrovascularabnormalities |