Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation

As the most common sustained arrhythmia, AF is a complex clinical entity which remains a difficult condition to durably treat in the majority of patients. Over the past few decades, the management of AF has focused mainly on pulmonary vein triggers for its initiation and perpetuation. It is well kno...

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Main Authors: Tolga Aksu, Jamario R Skeete, Henry H Huang
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-01-01
Series:Arrhythmia & Electrophysiology Review
Online Access:https://www.aerjournal.com/articles/ganglionic-plexus-ablation-step-step-guide-electrophysiologists-and-review-modalities
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author Tolga Aksu
Jamario R Skeete
Henry H Huang
author_facet Tolga Aksu
Jamario R Skeete
Henry H Huang
author_sort Tolga Aksu
collection DOAJ
description As the most common sustained arrhythmia, AF is a complex clinical entity which remains a difficult condition to durably treat in the majority of patients. Over the past few decades, the management of AF has focused mainly on pulmonary vein triggers for its initiation and perpetuation. It is well known that the autonomic nervous system (ANS) has a significant role in the milieu predisposing to the triggers, perpetuators and substrate for AF. Neuromodulation of ANS – ganglionated plexus ablation, vein of Marshall ethanol infusion, transcutaneous tragal stimulation, renal nerve denervation, stellate ganglion block and baroreceptor stimulation – constitute an emerging therapeutic approach for AF. The purpose of this review is to summarise and critically appraise the currently available evidence for neuromodulation modalities in AF.
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spelling doaj.art-1954f7980d9245899936cb067a9201c42023-03-11T16:04:56ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33692050-33772023-01-011210.15420/aer.2022.37Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial FibrillationTolga Aksu0Jamario R Skeete1Henry H Huang2Department of Cardiology, Yeditepe University Hospital, Istanbul, TurkeyDepartment of Cardiology, Rush Medical College, Chicago, IL, USDepartment of Cardiology, Rush Medical College, Chicago, IL, USAs the most common sustained arrhythmia, AF is a complex clinical entity which remains a difficult condition to durably treat in the majority of patients. Over the past few decades, the management of AF has focused mainly on pulmonary vein triggers for its initiation and perpetuation. It is well known that the autonomic nervous system (ANS) has a significant role in the milieu predisposing to the triggers, perpetuators and substrate for AF. Neuromodulation of ANS – ganglionated plexus ablation, vein of Marshall ethanol infusion, transcutaneous tragal stimulation, renal nerve denervation, stellate ganglion block and baroreceptor stimulation – constitute an emerging therapeutic approach for AF. The purpose of this review is to summarise and critically appraise the currently available evidence for neuromodulation modalities in AF.https://www.aerjournal.com/articles/ganglionic-plexus-ablation-step-step-guide-electrophysiologists-and-review-modalities
spellingShingle Tolga Aksu
Jamario R Skeete
Henry H Huang
Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
Arrhythmia & Electrophysiology Review
title Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
title_full Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
title_fullStr Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
title_full_unstemmed Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
title_short Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
title_sort ganglionic plexus ablation a step by step guide for electrophysiologists and review of modalities for neuromodulation for the management of atrial fibrillation
url https://www.aerjournal.com/articles/ganglionic-plexus-ablation-step-step-guide-electrophysiologists-and-review-modalities
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