Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation
As the most common sustained arrhythmia, AF is a complex clinical entity which remains a difficult condition to durably treat in the majority of patients. Over the past few decades, the management of AF has focused mainly on pulmonary vein triggers for its initiation and perpetuation. It is well kno...
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Format: | Article |
Language: | English |
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Radcliffe Medical Media
2023-01-01
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Series: | Arrhythmia & Electrophysiology Review |
Online Access: | https://www.aerjournal.com/articles/ganglionic-plexus-ablation-step-step-guide-electrophysiologists-and-review-modalities |
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author | Tolga Aksu Jamario R Skeete Henry H Huang |
author_facet | Tolga Aksu Jamario R Skeete Henry H Huang |
author_sort | Tolga Aksu |
collection | DOAJ |
description | As the most common sustained arrhythmia, AF is a complex clinical entity which remains a difficult condition to durably treat in the majority of patients. Over the past few decades, the management of AF has focused mainly on pulmonary vein triggers for its initiation and perpetuation. It is well known that the autonomic nervous system (ANS) has a significant role in the milieu predisposing to the triggers, perpetuators and substrate for AF. Neuromodulation of ANS – ganglionated plexus ablation, vein of Marshall ethanol infusion, transcutaneous tragal stimulation, renal nerve denervation, stellate ganglion block and baroreceptor stimulation – constitute an emerging therapeutic approach for AF. The purpose of this review is to summarise and critically appraise the currently available evidence for neuromodulation modalities in AF. |
first_indexed | 2024-04-10T04:17:54Z |
format | Article |
id | doaj.art-1954f7980d9245899936cb067a9201c4 |
institution | Directory Open Access Journal |
issn | 2050-3369 2050-3377 |
language | English |
last_indexed | 2024-04-10T04:17:54Z |
publishDate | 2023-01-01 |
publisher | Radcliffe Medical Media |
record_format | Article |
series | Arrhythmia & Electrophysiology Review |
spelling | doaj.art-1954f7980d9245899936cb067a9201c42023-03-11T16:04:56ZengRadcliffe Medical MediaArrhythmia & Electrophysiology Review2050-33692050-33772023-01-011210.15420/aer.2022.37Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial FibrillationTolga Aksu0Jamario R Skeete1Henry H Huang2Department of Cardiology, Yeditepe University Hospital, Istanbul, TurkeyDepartment of Cardiology, Rush Medical College, Chicago, IL, USDepartment of Cardiology, Rush Medical College, Chicago, IL, USAs the most common sustained arrhythmia, AF is a complex clinical entity which remains a difficult condition to durably treat in the majority of patients. Over the past few decades, the management of AF has focused mainly on pulmonary vein triggers for its initiation and perpetuation. It is well known that the autonomic nervous system (ANS) has a significant role in the milieu predisposing to the triggers, perpetuators and substrate for AF. Neuromodulation of ANS – ganglionated plexus ablation, vein of Marshall ethanol infusion, transcutaneous tragal stimulation, renal nerve denervation, stellate ganglion block and baroreceptor stimulation – constitute an emerging therapeutic approach for AF. The purpose of this review is to summarise and critically appraise the currently available evidence for neuromodulation modalities in AF.https://www.aerjournal.com/articles/ganglionic-plexus-ablation-step-step-guide-electrophysiologists-and-review-modalities |
spellingShingle | Tolga Aksu Jamario R Skeete Henry H Huang Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation Arrhythmia & Electrophysiology Review |
title | Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation |
title_full | Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation |
title_fullStr | Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation |
title_full_unstemmed | Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation |
title_short | Ganglionic Plexus Ablation: A Step-by-step Guide for Electrophysiologists and Review of Modalities for Neuromodulation for the Management of Atrial Fibrillation |
title_sort | ganglionic plexus ablation a step by step guide for electrophysiologists and review of modalities for neuromodulation for the management of atrial fibrillation |
url | https://www.aerjournal.com/articles/ganglionic-plexus-ablation-step-step-guide-electrophysiologists-and-review-modalities |
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