From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic

From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic

Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria. However, determining its origin, ecosystem roles, and biomedical applications has challenged researchers for decades. Recognized as a...

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Bibliographic Details
Main Authors: Gary M. Bucciarelli, Maren Lechner, Audrey Fontes, Lee B. Kats, Heather L. Eisthen, H. Bradley Shaffer
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Toxins
Subjects:
tetrodotoxin
TTX
neurotoxin
sodium channel
analgesic
therapeutic
Online Access:https://www.mdpi.com/2072-6651/13/8/517

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