Immunity in patients long occupationally exposed to tuberculosis infection
Objective: to study the impact of long-term occupational exposure to tuberculosis infection on the immune response of tuberculosis hospital workers. In this category of people versus tuberculin-positive persons having no household or occupational contacts, the investigators assessed the results of D...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2014-12-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/316 |
| Summary: | Objective: to study the impact of long-term occupational exposure to tuberculosis infection on the immune response of tuberculosis hospital workers. In this category of people versus tuberculin-positive persons having no household or occupational contacts, the investigators assessed the results of Diaskintest and determined the spontaneous and H37Rv and ESAT-6 antigen-stimulated production of IFN-γ and anti-M. tuberculosis antibodies in peripheral blood. The functional abilities of immunocompetent cells were not established to be exhausted in the workers of tuberculosis institutions due to their long-term contact with M. tuberculosis-excreting patients; however, among these examinees, there was a group of patients who had latent tuberculosis infection and needed preventive measures against active tuberculosis. |
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| ISSN: | 2075-1230 2542-1506 |