Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study
Background: Turmeric is a naturally occurring polyphenol that alleviates many diseases. The main phytochemical in them is curcumin which has anti-inflammatory, antioxidant, antiseptic, and analgesic properties. Poor solubility and bioavailability due to its hydrophobic nature are its drawback. Objec...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Indian Academy of Oral Medicine and Radiology |
| Subjects: | |
| Online Access: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=3;spage=299;epage=305;aulast=Dharman |
| _version_ | 1797645616174596096 |
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| author | Sreedevi Dharman Gopal Maragathavalli Rajeshkumar Shanmugam Karpagavalli Shanmugasundaram |
| author_facet | Sreedevi Dharman Gopal Maragathavalli Rajeshkumar Shanmugam Karpagavalli Shanmugasundaram |
| author_sort | Sreedevi Dharman |
| collection | DOAJ |
| description | Background: Turmeric is a naturally occurring polyphenol that alleviates many diseases. The main phytochemical in them is curcumin which has anti-inflammatory, antioxidant, antiseptic, and analgesic properties. Poor solubility and bioavailability due to its hydrophobic nature are its drawback. Objectives: This research aimed to green synthesize silver nanoparticles (AgNPs) using turmeric extract and to analyze its antioxidant, anti-inflammatory, and antimicrobial potential among oral pathogens. Materials and Methods: Turmeric silver nanoparticles (TuAgNPs) were analyzed by UV-visible spectrophotometer (UV-Vis) and transmission electron microscopy (TEM). Antioxidant, anti-inflammatory, and antimicrobial activity against oral pathogens were evaluated. Results: UV-visible spectrophotometry of TuAgNPs showed its maximum absorption peak at 440 nm. TEM image exhibited spherical-shaped AgNPs with a size of about 30 nm. They showed 88% strong antioxidant and 83% anti-inflammatory activities at 50 μg/mL. Biosynthesized TuAgNPs showed its potent effect against Streptococcus mutans, Staphylococcus aureus, Candida albicans at 25 μg/mL, and Enterococcus faecalis at 50 μg/mL. Conclusion: The development of effective green-synthesized TuAgNPs showed strong antioxidant, anti-inflammatory, and broad spectrum antimicrobial potential against oral pathogens. Biosynthesis of novel TuAgNPs could be efficiently utilized in the application of treating various oral mucosal lesions. |
| first_indexed | 2024-03-11T14:49:25Z |
| format | Article |
| id | doaj.art-195c8157840d40d494dff0a9f35f7099 |
| institution | Directory Open Access Journal |
| issn | 0972-1363 |
| language | English |
| last_indexed | 2024-03-11T14:49:25Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Academy of Oral Medicine and Radiology |
| spelling | doaj.art-195c8157840d40d494dff0a9f35f70992023-10-30T10:03:33ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632023-01-0135329930510.4103/jiaomr.jiaomr_309_22Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro studySreedevi DharmanGopal MaragathavalliRajeshkumar ShanmugamKarpagavalli ShanmugasundaramBackground: Turmeric is a naturally occurring polyphenol that alleviates many diseases. The main phytochemical in them is curcumin which has anti-inflammatory, antioxidant, antiseptic, and analgesic properties. Poor solubility and bioavailability due to its hydrophobic nature are its drawback. Objectives: This research aimed to green synthesize silver nanoparticles (AgNPs) using turmeric extract and to analyze its antioxidant, anti-inflammatory, and antimicrobial potential among oral pathogens. Materials and Methods: Turmeric silver nanoparticles (TuAgNPs) were analyzed by UV-visible spectrophotometer (UV-Vis) and transmission electron microscopy (TEM). Antioxidant, anti-inflammatory, and antimicrobial activity against oral pathogens were evaluated. Results: UV-visible spectrophotometry of TuAgNPs showed its maximum absorption peak at 440 nm. TEM image exhibited spherical-shaped AgNPs with a size of about 30 nm. They showed 88% strong antioxidant and 83% anti-inflammatory activities at 50 μg/mL. Biosynthesized TuAgNPs showed its potent effect against Streptococcus mutans, Staphylococcus aureus, Candida albicans at 25 μg/mL, and Enterococcus faecalis at 50 μg/mL. Conclusion: The development of effective green-synthesized TuAgNPs showed strong antioxidant, anti-inflammatory, and broad spectrum antimicrobial potential against oral pathogens. Biosynthesis of novel TuAgNPs could be efficiently utilized in the application of treating various oral mucosal lesions.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=3;spage=299;epage=305;aulast=Dharmananti-inflammatoryantimicrobial activityantioxidantsilver nanoparticlesturmeric extract |
| spellingShingle | Sreedevi Dharman Gopal Maragathavalli Rajeshkumar Shanmugam Karpagavalli Shanmugasundaram Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study Journal of Indian Academy of Oral Medicine and Radiology anti-inflammatory antimicrobial activity antioxidant silver nanoparticles turmeric extract |
| title | Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study |
| title_full | Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study |
| title_fullStr | Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study |
| title_full_unstemmed | Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study |
| title_short | Biosynthesis of turmeric silver nanoparticles: Its characterization and evaluation of antioxidant, anti inflammatory, antimicrobial potential against oral pathogens an In vitro study |
| title_sort | biosynthesis of turmeric silver nanoparticles its characterization and evaluation of antioxidant anti inflammatory antimicrobial potential against oral pathogens an in vitro study |
| topic | anti-inflammatory antimicrobial activity antioxidant silver nanoparticles turmeric extract |
| url | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2023;volume=35;issue=3;spage=299;epage=305;aulast=Dharman |
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