Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport

Pseudorabies Virus Mutants Lacking US9 Are Defective in Cytoplasmic Assembly and Sorting of Virus Particles into Axons and Not in Axonal Transport

Herpes simplex virus (HSV) and varicella zoster virus (VZV) rely on transport of virus particles in neuronal axons to spread from sites of viral latency in sensory ganglia to peripheral tissues then on to other hosts. This process of anterograde axonal transport involves kinesin motors that move vir...

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Bibliographic Details
Main Authors: Steven Adamou, Adam Vanarsdall, David C. Johnson
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
neurons
anterograde transport
axons
gE/gI
assembly
sorting
Online Access:https://www.mdpi.com/1999-4915/15/1/153

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