Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study

Introduction: Compared to ordinary people, addicts usually have a lower pain threshold. The current work attempts to compare the performance of local analgesia with lidocaine among opium addicts and non-addicts. Methods: In this case-control study, opium addicts and healthy patients with skin lac...

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Main Authors: Alireza Majidi, Tala Shahhosseini, Sadrolla Mahmoudi
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2018-06-01
Series:Archives of Academic Emergency Medicine
Subjects:
Online Access:https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/78
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author Alireza Majidi
Tala Shahhosseini
Sadrolla Mahmoudi
author_facet Alireza Majidi
Tala Shahhosseini
Sadrolla Mahmoudi
author_sort Alireza Majidi
collection DOAJ
description Introduction: Compared to ordinary people, addicts usually have a lower pain threshold. The current work attempts to compare the performance of local analgesia with lidocaine among opium addicts and non-addicts. Methods: In this case-control study, opium addicts and healthy patients with skin laceration referring to emergency departments of two educational hospitals were compared regarding the response to local anesthesia with lidocaine, as well as side effects. Results: 197 cases with the mean age of 43.44 ± 20.12 years were studied (72.1% male). 98 (49.8%) cases were addicts and 99 (50.2%) were healthy people. Two groups were similar regarding age (p = 0.281), sex (p = 0.666), and wound size (p = 0.272). The amount of pain reduction 5 (df =1.5, F=0.38, p = 0.88) and 10 (df =1.5, F=0.58, p = 0.72) minutes after lidocaine injection was not different between the groups. Subgroup analysis based on sex and age of patient did not show any differences between the groups (p > 0.1 for all analysis). The mean duration of analgesia was 16.4 ± 5.37 minutes in addicts and 16.95±1.79 in control group (p = 0.334). Conclusion: Lidocaine, as a commonly used local anesthetic agents, does not show different effects in addicts and non-addicts in repairing skin laceration.
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spelling doaj.art-195dec8fd1bf4f888ade65bdd96c7cd92022-12-22T00:38:24ZengShahid Beheshti University of Medical SciencesArchives of Academic Emergency Medicine2645-49042018-06-016110.22037/aaem.v6i1.78Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control StudyAlireza Majidi0Tala Shahhosseini1Sadrolla Mahmoudi2Emergency Department, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranEmergency Department, Shohadaye Pakdasht Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranEmergency Department, Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Tehran, IranIntroduction: Compared to ordinary people, addicts usually have a lower pain threshold. The current work attempts to compare the performance of local analgesia with lidocaine among opium addicts and non-addicts. Methods: In this case-control study, opium addicts and healthy patients with skin laceration referring to emergency departments of two educational hospitals were compared regarding the response to local anesthesia with lidocaine, as well as side effects. Results: 197 cases with the mean age of 43.44 ± 20.12 years were studied (72.1% male). 98 (49.8%) cases were addicts and 99 (50.2%) were healthy people. Two groups were similar regarding age (p = 0.281), sex (p = 0.666), and wound size (p = 0.272). The amount of pain reduction 5 (df =1.5, F=0.38, p = 0.88) and 10 (df =1.5, F=0.58, p = 0.72) minutes after lidocaine injection was not different between the groups. Subgroup analysis based on sex and age of patient did not show any differences between the groups (p > 0.1 for all analysis). The mean duration of analgesia was 16.4 ± 5.37 minutes in addicts and 16.95±1.79 in control group (p = 0.334). Conclusion: Lidocaine, as a commonly used local anesthetic agents, does not show different effects in addicts and non-addicts in repairing skin laceration.https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/78Lidocaineopium dependenceanestheticslocalcase-control studiespain management
spellingShingle Alireza Majidi
Tala Shahhosseini
Sadrolla Mahmoudi
Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study
Archives of Academic Emergency Medicine
Lidocaine
opium dependence
anesthetics
local
case-control studies
pain management
title Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study
title_full Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study
title_fullStr Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study
title_full_unstemmed Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study
title_short Performance of Local Anesthesia with Lidocaine among Opium Addicts and Non-Addicts; a Case Control Study
title_sort performance of local anesthesia with lidocaine among opium addicts and non addicts a case control study
topic Lidocaine
opium dependence
anesthetics
local
case-control studies
pain management
url https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/78
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AT sadrollamahmoudi performanceoflocalanesthesiawithlidocaineamongopiumaddictsandnonaddictsacasecontrolstudy