Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era
ABSTRACT Purpose: The aim of this work is to review and synthesize the existing evidence and recommendations regarding to the therapeutic and surgical indications as well as monitoring of patients with Penile Cancer in COVID-19 era and to propose an action protocol to facilitate decision-making. M...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Urologia
2020-07-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382020000700086&tlng=en |
| _version_ | 1798022030269874176 |
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| author | Nelson Canales Casco María Jiménez Carmona Álvaro Juárez Soto |
| author_facet | Nelson Canales Casco María Jiménez Carmona Álvaro Juárez Soto |
| author_sort | Nelson Canales Casco |
| collection | DOAJ |
| description | ABSTRACT Purpose: The aim of this work is to review and synthesize the existing evidence and recommendations regarding to the therapeutic and surgical indications as well as monitoring of patients with Penile Cancer in COVID-19 era and to propose an action protocol to facilitate decision-making. Material and Methods: A non-systematic review of the literature regarding the management of penile cancer during the COVID-19 pandemic was performed until April 30, 2020. We propose our recommendations based on this evidence. Results: Penile cancer is an uncommon but aggressive disease. Prognosis is determined by several characteristics, being the most important the presence of lymph nodes, in which case, treatment should not be delayed. For these reasons, an initial evaluation is mandatory. Priority classifications, based on the oncological outcomes when treatment is delayed, have been made in order to separate deferrable disease from the one that needs high priority treatment. In penile cancer with low risk of progression, surgical treatment can be delayed, but other options must be considered, like topical treatment or laser therapy. In cases with intermediate risk of progression, surgical treatment may be delayed up to three months, but we must consider radiation therapy and brachytherapy as effective options. When feasible, follow-up should by telemonitoring. Conclusions: In the COVID 19 era, initial evaluation of the patient is mandatory. Histological diagnosis with local staging is necessary before offering any therapeutic option. In case of superficial non-invasive disease, topical treatment is effective in absence of lymph node involvement. In selected patients, radiotherapy is an organpreserving approach with good results. Non-deferrable surgical treatment must be performed by an experienced surgeon and as an outpatient procedure when possible. When indicated, iLND should not be delayed since it is decisive for patient survival. Follow-up should be by telemonitoring. |
| first_indexed | 2024-04-11T17:23:09Z |
| format | Article |
| id | doaj.art-19614e139304492c9808627eefa55939 |
| institution | Directory Open Access Journal |
| issn | 1677-6119 |
| language | English |
| last_indexed | 2024-04-11T17:23:09Z |
| publishDate | 2020-07-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-19614e139304492c9808627eefa559392022-12-22T04:12:25ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192020-07-0146suppl 1869210.1590/s1677-5538.ibju.2020.s110Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 eraNelson Canales Cascohttps://orcid.org/0000-0002-5458-7615María Jiménez CarmonaÁlvaro Juárez SotoABSTRACT Purpose: The aim of this work is to review and synthesize the existing evidence and recommendations regarding to the therapeutic and surgical indications as well as monitoring of patients with Penile Cancer in COVID-19 era and to propose an action protocol to facilitate decision-making. Material and Methods: A non-systematic review of the literature regarding the management of penile cancer during the COVID-19 pandemic was performed until April 30, 2020. We propose our recommendations based on this evidence. Results: Penile cancer is an uncommon but aggressive disease. Prognosis is determined by several characteristics, being the most important the presence of lymph nodes, in which case, treatment should not be delayed. For these reasons, an initial evaluation is mandatory. Priority classifications, based on the oncological outcomes when treatment is delayed, have been made in order to separate deferrable disease from the one that needs high priority treatment. In penile cancer with low risk of progression, surgical treatment can be delayed, but other options must be considered, like topical treatment or laser therapy. In cases with intermediate risk of progression, surgical treatment may be delayed up to three months, but we must consider radiation therapy and brachytherapy as effective options. When feasible, follow-up should by telemonitoring. Conclusions: In the COVID 19 era, initial evaluation of the patient is mandatory. Histological diagnosis with local staging is necessary before offering any therapeutic option. In case of superficial non-invasive disease, topical treatment is effective in absence of lymph node involvement. In selected patients, radiotherapy is an organpreserving approach with good results. Non-deferrable surgical treatment must be performed by an experienced surgeon and as an outpatient procedure when possible. When indicated, iLND should not be delayed since it is decisive for patient survival. Follow-up should be by telemonitoring.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382020000700086&tlng=enPenile NeoplasmsClinical ProtocolsCOVID-19 [Supplementary Concept]Pandemics |
| spellingShingle | Nelson Canales Casco María Jiménez Carmona Álvaro Juárez Soto Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era International Brazilian Journal of Urology Penile Neoplasms Clinical Protocols COVID-19 [Supplementary Concept] Pandemics |
| title | Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era |
| title_full | Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era |
| title_fullStr | Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era |
| title_full_unstemmed | Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era |
| title_short | Therapeutic and Surgical Indications for Patients with Penile Cancer in the COVID-19 era |
| title_sort | therapeutic and surgical indications for patients with penile cancer in the covid 19 era |
| topic | Penile Neoplasms Clinical Protocols COVID-19 [Supplementary Concept] Pandemics |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382020000700086&tlng=en |
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