Multifunctional Role of Lipids in Modulating the Tumorigenic Properties of 4T1 Breast Cancer Cells

Multifunctional Role of Lipids in Modulating the Tumorigenic Properties of 4T1 Breast Cancer Cells

Tumor growth and progression are linked to an altered lipid metabolism in the tumor microenvironment (TME), including tumor cells and tumor-associated macrophages (TAMs). A growing number of lipid metabolism targeting drugs have shown efficacy in anti-tumor therapy. In addition, exogenously applied...

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Bibliographic Details
Main Authors: Yuanyuan He, Somayeh Rezaei, Raimundo Fernandes de Araújo Júnior, Luis J. Cruz, Christina Eich
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
tumor-associated macrophages
M2 macrophages
palmitic acid
ceramide
sphingomyelin
docosahexaenoic acid
Online Access:https://www.mdpi.com/1422-0067/23/8/4240

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