Total plasma homocysteine measurement: Evaluation of the Abbott immunoassay, comparison with the JEOL ion exchange chromatography and investigation of its clinical utility

Total plasma homocysteine measurement: Evaluation of the Abbott immunoassay, comparison with the JEOL ion exchange chromatography and investigation of its clinical utility

Objectives: Homocysteine is an intermediary amino acid formed in methionine metabolism, with elevated total homocysteine (tHCY) being a biomarker of cardiovascular and cerebrovascular diseases. We evaluated the Abbott ARCHITECT tHCY immunoassay, compared it with the current established JEOL ion exch...

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Bibliographic Details
Main Authors: Kai Fung Kevin Suen, Graham R. Lee, Michelle Finnegan, Kieran Halton, Ingrid Borovickova, Caoilfionn Trench, Maria C. Fitzgibbon
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Practical Laboratory Medicine
Subjects:
Homocysteine
Immunoassay
ion exchange chromatography
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551722000348

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