Photoluminescent porous silicon nanowires as contrast agents for bioimaging
Porous silicon nanowires (pSi NWs) have attracted considerable interest due to their unique structural, optical properties and biocompatibility. The most common method for their top-down synthesis is metal-assisted chemical etching (MACE) of crystalline silicon (c-Si) wafers using silver nanoparticl...
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| Format: | Article |
| Language: | English |
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Voronezh State University
2024-03-01
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| Series: | Конденсированные среды и межфазные границы |
| Subjects: | |
| Online Access: | https://journals.vsu.ru/kcmf/article/view/11819/11992 |
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| author | Maria G. Shatskaia Daria A. Nazarovskaia Kirill A. Gonchar Yana V. Lomovskaya Ilia I. Tsiniaikin Olga A. Shalygina Andrey A. Kudryavtsev Liubov A. Osminkina |
| author_facet | Maria G. Shatskaia Daria A. Nazarovskaia Kirill A. Gonchar Yana V. Lomovskaya Ilia I. Tsiniaikin Olga A. Shalygina Andrey A. Kudryavtsev Liubov A. Osminkina |
| author_sort | Maria G. Shatskaia |
| collection | DOAJ |
| description | Porous silicon nanowires (pSi NWs) have attracted considerable interest due to their unique structural, optical properties and biocompatibility. The most common method for their top-down synthesis is metal-assisted chemical etching (MACE) of crystalline silicon (c-Si) wafers using silver nanoparticles as a catalyst. However, the replacement of silver with bioinert gold nanoparticles (Au NPs) markedly improves the efficiency of pSi NWs in biomedical applications. The present study demonstrates the fabrication of porous pSi NWs arrays using Au NPs as the catalyst in MACE of c-Si wafers with a resistivity of 1–5 mOhm·cm. Using scanning electron microscopy (SEM), the formation of arrays of porous nanowires with a diameter of 50 nm that consist of small silicon nanocrystals (nc-Si) and pores was observed. Raman spectroscopy analysis determined the size of nc-Si is about 4 nm. The pSi NWs exhibit effective photoluminescence (PL) with a peak in the red spectrum, which is attributed to the quantum confinement effect occurred in small 4 nm nc-Si. In addition, the pSi NWs exhibit low toxicity towards MCF-7 cancer cells, and their PL characteristics allow them to be used as contrast agents for bioimaging |
| first_indexed | 2024-04-24T12:30:19Z |
| format | Article |
| id | doaj.art-1967968b8c164374ab806b9ba5ff9936 |
| institution | Directory Open Access Journal |
| issn | 1606-867X |
| language | English |
| last_indexed | 2024-04-24T12:30:19Z |
| publishDate | 2024-03-01 |
| publisher | Voronezh State University |
| record_format | Article |
| series | Конденсированные среды и межфазные границы |
| spelling | doaj.art-1967968b8c164374ab806b9ba5ff99362024-04-08T05:59:41ZengVoronezh State UniversityКонденсированные среды и межфазные границы1606-867X2024-03-0126110.17308/kcmf.2024.26/11819Photoluminescent porous silicon nanowires as contrast agents for bioimagingMaria G. Shatskaia0Daria A. Nazarovskaia1https://orcid.org/0000-0001-8151-9602Kirill A. Gonchar2https://orcid.org/0000-0002-2301-2886Yana V. Lomovskaya3Ilia I. Tsiniaikin4https://orcid.org/0000-0002-5820-8774Olga A. Shalygina5https://orcid.org/0000-0002-0067-318XAndrey A. Kudryavtsev6Liubov A. Osminkina7https://orcid.org/0000-0001-7485-0495Lomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian Federation; Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences, 3 Institutskaya str., Pushchino 142290, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian Federation; Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences, 3 Institutskaya str., Pushchino 142290, Russian Federation; Institute for Biological Instrumentation of the Russian Academy of Sciences, 7 Institutskaya str., Pushchino 142290, Russian FederationLomonosov Moscow State University, Faculty of Physics, 1 Leninskie Gory, Moscow 119991, Russian Federation; Institute for Biological Instrumentation of the Russian Academy of Sciences, 7 Institutskaya str., Pushchino 142290, Russian FederationPorous silicon nanowires (pSi NWs) have attracted considerable interest due to their unique structural, optical properties and biocompatibility. The most common method for their top-down synthesis is metal-assisted chemical etching (MACE) of crystalline silicon (c-Si) wafers using silver nanoparticles as a catalyst. However, the replacement of silver with bioinert gold nanoparticles (Au NPs) markedly improves the efficiency of pSi NWs in biomedical applications. The present study demonstrates the fabrication of porous pSi NWs arrays using Au NPs as the catalyst in MACE of c-Si wafers with a resistivity of 1–5 mOhm·cm. Using scanning electron microscopy (SEM), the formation of arrays of porous nanowires with a diameter of 50 nm that consist of small silicon nanocrystals (nc-Si) and pores was observed. Raman spectroscopy analysis determined the size of nc-Si is about 4 nm. The pSi NWs exhibit effective photoluminescence (PL) with a peak in the red spectrum, which is attributed to the quantum confinement effect occurred in small 4 nm nc-Si. In addition, the pSi NWs exhibit low toxicity towards MCF-7 cancer cells, and their PL characteristics allow them to be used as contrast agents for bioimaginghttps://journals.vsu.ru/kcmf/article/view/11819/11992porous silicon nanowiresphotoluminescenceraman spectroscopycontrast agentsbioimaging |
| spellingShingle | Maria G. Shatskaia Daria A. Nazarovskaia Kirill A. Gonchar Yana V. Lomovskaya Ilia I. Tsiniaikin Olga A. Shalygina Andrey A. Kudryavtsev Liubov A. Osminkina Photoluminescent porous silicon nanowires as contrast agents for bioimaging Конденсированные среды и межфазные границы porous silicon nanowires photoluminescence raman spectroscopy contrast agents bioimaging |
| title | Photoluminescent porous silicon nanowires as contrast agents for bioimaging |
| title_full | Photoluminescent porous silicon nanowires as contrast agents for bioimaging |
| title_fullStr | Photoluminescent porous silicon nanowires as contrast agents for bioimaging |
| title_full_unstemmed | Photoluminescent porous silicon nanowires as contrast agents for bioimaging |
| title_short | Photoluminescent porous silicon nanowires as contrast agents for bioimaging |
| title_sort | photoluminescent porous silicon nanowires as contrast agents for bioimaging |
| topic | porous silicon nanowires photoluminescence raman spectroscopy contrast agents bioimaging |
| url | https://journals.vsu.ru/kcmf/article/view/11819/11992 |
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