Histone Deacetylase Inhibitors Downregulate Calcium Pyrophosphate Crystal Formation in Human Articular Chondrocytes

Histone Deacetylase Inhibitors Downregulate Calcium Pyrophosphate Crystal Formation in Human Articular Chondrocytes

Calcium pyrophosphate (CPP) deposition disease (CPPD) is a form of CPP crystal-induced arthritis. A high concentration of extracellular pyrophosphate (ePPi) in synovial fluid is positively correlated with the formation of CPP crystals, and ePPi can be upregulated by ankylosis human (ANKH) and ectonu...

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Bibliographic Details
Main Authors:	Chi-Ching Chang, Kun-Lin Lee, Tze-Sian Chan, Chia-Chen Chung, Yu-Chih Liang
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	International Journal of Molecular Sciences
Subjects:	calcium pyrophosphate HDAC ANKH ENPP1 TNAP
Online Access:	https://www.mdpi.com/1422-0067/23/5/2604

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