Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism.

Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism.

Venous thromboembolism (VTE) is a major cause of morbidity and mortality in elderly patients. Extracellular DNA is a pro-inflammatory and pro-thrombotic mediator in vitro and in animal models. Levels of circulating extracellular DNA (ceDNA) are increased in VTE patients, but the association of ceDNA...

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Main Authors: Miguel Jiménez-Alcázar, Andreas Limacher, Rachita Panda, Marie Méan, Josephine Bitterling, Sven Peine, Thomas Renné, Jürg H Beer, Drahomir Aujesky, Bernhard Lämmle, Tobias A Fuchs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5825008?pdf=render

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