Fluoxetine-related ecchymosis treated with venlafaxine: a case report
Selective serotonin reuptake inhibitors (SSRIs) are known to have a relatively favourable side effect profile. In recent years, there has been an emphasis on the risk of upper gastrointestinal bleeding in patients taking SSRI antidepressants. Although they may have some effects on coagulation profil...
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Format: | Article |
Language: | English |
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AVES
2017-10-01
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Series: | Psychiatry and Clinical Psychopharmacology |
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Online Access: | http://dx.doi.org/10.1080/24750573.2017.1367556 |
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author | Hakan Karaş Taner Yılmaz |
author_facet | Hakan Karaş Taner Yılmaz |
author_sort | Hakan Karaş |
collection | DOAJ |
description | Selective serotonin reuptake inhibitors (SSRIs) are known to have a relatively favourable side effect profile. In recent years, there has been an emphasis on the risk of upper gastrointestinal bleeding in patients taking SSRI antidepressants. Although they may have some effects on coagulation profile, ecchymosis is a rare clinical manifestation of these effects. Here, we report a 25-year-old female patient who was diagnosed with major depressive disorder and manifested spontaneous ecchymoses on her legs rapidly following fluoxetine use. Her complete blood cell count, prothrombin time, partial thromboplastin time, bleeding time, and other hematological screening tests were within normal limits. After discontinuation of fluoxetine, her ecchymoses were resolved in two weeks. Ecchymosis did not recur after fluoxetine was discontinued, and the patient was switched to venlafaxine. |
first_indexed | 2024-04-10T11:53:25Z |
format | Article |
id | doaj.art-196d3c6ad4024da19340aea82a5665b6 |
institution | Directory Open Access Journal |
issn | 2475-0573 2475-0581 |
language | English |
last_indexed | 2024-04-10T11:53:25Z |
publishDate | 2017-10-01 |
publisher | AVES |
record_format | Article |
series | Psychiatry and Clinical Psychopharmacology |
spelling | doaj.art-196d3c6ad4024da19340aea82a5665b62023-02-15T16:16:59ZengAVESPsychiatry and Clinical Psychopharmacology2475-05732475-05812017-10-0127440941110.1080/24750573.2017.13675561367556Fluoxetine-related ecchymosis treated with venlafaxine: a case reportHakan Karaş0Taner Yılmaz1Beykent UniversityMiddle East Technical University Northern Cyprus CampusSelective serotonin reuptake inhibitors (SSRIs) are known to have a relatively favourable side effect profile. In recent years, there has been an emphasis on the risk of upper gastrointestinal bleeding in patients taking SSRI antidepressants. Although they may have some effects on coagulation profile, ecchymosis is a rare clinical manifestation of these effects. Here, we report a 25-year-old female patient who was diagnosed with major depressive disorder and manifested spontaneous ecchymoses on her legs rapidly following fluoxetine use. Her complete blood cell count, prothrombin time, partial thromboplastin time, bleeding time, and other hematological screening tests were within normal limits. After discontinuation of fluoxetine, her ecchymoses were resolved in two weeks. Ecchymosis did not recur after fluoxetine was discontinued, and the patient was switched to venlafaxine.http://dx.doi.org/10.1080/24750573.2017.1367556Fluoxetineecchymosisside effect |
spellingShingle | Hakan Karaş Taner Yılmaz Fluoxetine-related ecchymosis treated with venlafaxine: a case report Psychiatry and Clinical Psychopharmacology Fluoxetine ecchymosis side effect |
title | Fluoxetine-related ecchymosis treated with venlafaxine: a case report |
title_full | Fluoxetine-related ecchymosis treated with venlafaxine: a case report |
title_fullStr | Fluoxetine-related ecchymosis treated with venlafaxine: a case report |
title_full_unstemmed | Fluoxetine-related ecchymosis treated with venlafaxine: a case report |
title_short | Fluoxetine-related ecchymosis treated with venlafaxine: a case report |
title_sort | fluoxetine related ecchymosis treated with venlafaxine a case report |
topic | Fluoxetine ecchymosis side effect |
url | http://dx.doi.org/10.1080/24750573.2017.1367556 |
work_keys_str_mv | AT hakankaras fluoxetinerelatedecchymosistreatedwithvenlafaxineacasereport AT taneryılmaz fluoxetinerelatedecchymosistreatedwithvenlafaxineacasereport |