Fluoxetine-related ecchymosis treated with venlafaxine: a case report

Selective serotonin reuptake inhibitors (SSRIs) are known to have a relatively favourable side effect profile. In recent years, there has been an emphasis on the risk of upper gastrointestinal bleeding in patients taking SSRI antidepressants. Although they may have some effects on coagulation profil...

Full description

Bibliographic Details
Main Authors: Hakan Karaş, Taner Yılmaz
Format: Article
Language:English
Published: AVES 2017-10-01
Series:Psychiatry and Clinical Psychopharmacology
Subjects:
Online Access:http://dx.doi.org/10.1080/24750573.2017.1367556
_version_ 1828021449776955392
author Hakan Karaş
Taner Yılmaz
author_facet Hakan Karaş
Taner Yılmaz
author_sort Hakan Karaş
collection DOAJ
description Selective serotonin reuptake inhibitors (SSRIs) are known to have a relatively favourable side effect profile. In recent years, there has been an emphasis on the risk of upper gastrointestinal bleeding in patients taking SSRI antidepressants. Although they may have some effects on coagulation profile, ecchymosis is a rare clinical manifestation of these effects. Here, we report a 25-year-old female patient who was diagnosed with major depressive disorder and manifested spontaneous ecchymoses on her legs rapidly following fluoxetine use. Her complete blood cell count, prothrombin time, partial thromboplastin time, bleeding time, and other hematological screening tests were within normal limits. After discontinuation of fluoxetine, her ecchymoses were resolved in two weeks. Ecchymosis did not recur after fluoxetine was discontinued, and the patient was switched to venlafaxine.
first_indexed 2024-04-10T11:53:25Z
format Article
id doaj.art-196d3c6ad4024da19340aea82a5665b6
institution Directory Open Access Journal
issn 2475-0573
2475-0581
language English
last_indexed 2024-04-10T11:53:25Z
publishDate 2017-10-01
publisher AVES
record_format Article
series Psychiatry and Clinical Psychopharmacology
spelling doaj.art-196d3c6ad4024da19340aea82a5665b62023-02-15T16:16:59ZengAVESPsychiatry and Clinical Psychopharmacology2475-05732475-05812017-10-0127440941110.1080/24750573.2017.13675561367556Fluoxetine-related ecchymosis treated with venlafaxine: a case reportHakan Karaş0Taner Yılmaz1Beykent UniversityMiddle East Technical University Northern Cyprus CampusSelective serotonin reuptake inhibitors (SSRIs) are known to have a relatively favourable side effect profile. In recent years, there has been an emphasis on the risk of upper gastrointestinal bleeding in patients taking SSRI antidepressants. Although they may have some effects on coagulation profile, ecchymosis is a rare clinical manifestation of these effects. Here, we report a 25-year-old female patient who was diagnosed with major depressive disorder and manifested spontaneous ecchymoses on her legs rapidly following fluoxetine use. Her complete blood cell count, prothrombin time, partial thromboplastin time, bleeding time, and other hematological screening tests were within normal limits. After discontinuation of fluoxetine, her ecchymoses were resolved in two weeks. Ecchymosis did not recur after fluoxetine was discontinued, and the patient was switched to venlafaxine.http://dx.doi.org/10.1080/24750573.2017.1367556Fluoxetineecchymosisside effect
spellingShingle Hakan Karaş
Taner Yılmaz
Fluoxetine-related ecchymosis treated with venlafaxine: a case report
Psychiatry and Clinical Psychopharmacology
Fluoxetine
ecchymosis
side effect
title Fluoxetine-related ecchymosis treated with venlafaxine: a case report
title_full Fluoxetine-related ecchymosis treated with venlafaxine: a case report
title_fullStr Fluoxetine-related ecchymosis treated with venlafaxine: a case report
title_full_unstemmed Fluoxetine-related ecchymosis treated with venlafaxine: a case report
title_short Fluoxetine-related ecchymosis treated with venlafaxine: a case report
title_sort fluoxetine related ecchymosis treated with venlafaxine a case report
topic Fluoxetine
ecchymosis
side effect
url http://dx.doi.org/10.1080/24750573.2017.1367556
work_keys_str_mv AT hakankaras fluoxetinerelatedecchymosistreatedwithvenlafaxineacasereport
AT taneryılmaz fluoxetinerelatedecchymosistreatedwithvenlafaxineacasereport