Phenylthiazolidin-4-one piperazine Conjugates: Design, Synthesis, anticancer and antimicrobial studies

Phenylthiazolidin-4-one piperazine Conjugates: Design, Synthesis, anticancer and antimicrobial studies

In current research study, a series of ten novel phenylthiazolidin-4-one glycinamide conjugates with piperazines compounds (7a-j) were designed by combining the crucial pharmacophoric features from the reported potential anticancer hit molecules, subsequently evaluated for the drug-likeness behaviou...

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Bibliographic Details
Main Authors: Dalbir Singh, Rajiv Patel, Amit Aggarwal, Anwesha Das, Saurabh Sharma, Birasen Behera, Rajashree Panigrahy, Amanda R. Kirane, Harsha Kharkwal, Piyush Kumar, Naveen Prakash Bokolia, Murugesan Sankaranarayanan, Subhash Chander
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Anticancer
Antimicrobials
Drug-likeness
Piperazine
3D Spheroid models
4-Thiazolidinone
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623004769

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