ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT
Objective: To explore the profile of adverse events associated with interferon therapy. Design: Systematic review. Data sources: Electronic and paper records in subject area from 2000 to 2014. Methods: We searched for the studies on safety and tolerability containing adverse events of interferons wi...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-02-01
|
| Series: | Безопасность и риск фармакотерапии |
| Subjects: | |
| Online Access: | https://www.risksafety.ru/jour/article/view/10 |
| _version_ | 1797224584297054208 |
|---|---|
| author | A. A. Toporov A. S. Kolbin |
| author_facet | A. A. Toporov A. S. Kolbin |
| author_sort | A. A. Toporov |
| collection | DOAJ |
| description | Objective: To explore the profile of adverse events associated with interferon therapy. Design: Systematic review. Data sources: Electronic and paper records in subject area from 2000 to 2014. Methods: We searched for the studies on safety and tolerability containing adverse events of interferons with systemic effect. Results: The most frequent adverse events were: flu-like syndrome (55%), depression (30%), neutropenia (20%), anemia (13%). Conclusion: Adverse events are a very serious problem of interferon treatment. System of pharmacovigilance provides forecasting and early identification of these adverse events, as they are predictable. |
| first_indexed | 2024-03-08T22:27:04Z |
| format | Article |
| id | doaj.art-19705534fb8b4f59b37b56f9c3b3a18f |
| institution | Directory Open Access Journal |
| issn | 2312-7821 2619-1164 |
| language | Russian |
| last_indexed | 2024-04-24T13:55:26Z |
| publishDate | 2018-02-01 |
| publisher | Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» |
| record_format | Article |
| series | Безопасность и риск фармакотерапии |
| spelling | doaj.art-19705534fb8b4f59b37b56f9c3b3a18f2024-04-03T17:56:35ZrusMinistry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Безопасность и риск фармакотерапии2312-78212619-11642018-02-010251110ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECTA. A. Toporov0A. S. Kolbin1Pavlov First Saint Petersburg State Medical UniversityPavlov First Saint Petersburg State Medical University; Saint Petersburg State UniversityObjective: To explore the profile of adverse events associated with interferon therapy. Design: Systematic review. Data sources: Electronic and paper records in subject area from 2000 to 2014. Methods: We searched for the studies on safety and tolerability containing adverse events of interferons with systemic effect. Results: The most frequent adverse events were: flu-like syndrome (55%), depression (30%), neutropenia (20%), anemia (13%). Conclusion: Adverse events are a very serious problem of interferon treatment. System of pharmacovigilance provides forecasting and early identification of these adverse events, as they are predictable.https://www.risksafety.ru/jour/article/view/10нежелательные явленияинтерфероныфармаконадзорadverse eventpharmacovigilanceinterferonside effect |
| spellingShingle | A. A. Toporov A. S. Kolbin ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT Безопасность и риск фармакотерапии нежелательные явления интерфероны фармаконадзор adverse event pharmacovigilance interferon side effect |
| title | ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT |
| title_full | ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT |
| title_fullStr | ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT |
| title_full_unstemmed | ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT |
| title_short | ADVERSE EVENTS OF INTERFERONS WITH SYSTEMIC EFFECT |
| title_sort | adverse events of interferons with systemic effect |
| topic | нежелательные явления интерфероны фармаконадзор adverse event pharmacovigilance interferon side effect |
| url | https://www.risksafety.ru/jour/article/view/10 |
| work_keys_str_mv | AT aatoporov adverseeventsofinterferonswithsystemiceffect AT askolbin adverseeventsofinterferonswithsystemiceffect |