Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci

Abstract Background Anorexia nervosa (AN) is a polygenic, severe metabopsychiatric disorder with poorly understood aetiology. Eight significant loci have been identified by genome-wide association studies (GWAS) and single nucleotide polymorphism (SNP)-based heritability was estimated to be ~ 11–17,...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Natasha Berthold, Silvana Gaudieri, Sean Hood, Monika Tschochner, Allison L. Miller, Jennifer Jordan, Laura M. Thornton, Cynthia M. Bulik, Patrick Anthony Akkari, Martin A. Kennedy
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2024-12-01
Σειρά:BMC Genomics
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Διαθέσιμο Online:https://doi.org/10.1186/s12864-024-11172-7