Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci

Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci

Abstract Background Anorexia nervosa (AN) is a polygenic, severe metabopsychiatric disorder with poorly understood aetiology. Eight significant loci have been identified by genome-wide association studies (GWAS) and single nucleotide polymorphism (SNP)-based heritability was estimated to be ~ 11–17,...

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Hlavní autoři: Natasha Berthold, Silvana Gaudieri, Sean Hood, Monika Tschochner, Allison L. Miller, Jennifer Jordan, Laura M. Thornton, Cynthia M. Bulik, Patrick Anthony Akkari, Martin A. Kennedy
Médium: Článek
Jazyk:English
Vydáno: BMC 2024-12-01
Edice:BMC Genomics
Témata:
Eating disorders
Psychiatric genetics
Anorexia nervosa risk loci
Structural variants
Transposable elements
Nanopore sequencing
On-line přístup:https://doi.org/10.1186/s12864-024-11172-7

Internet

https://doi.org/10.1186/s12864-024-11172-7

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